ERCC6L antibody

Principal name

ERCC6L antibody

Alternative names for ERCC6L antibody

PICH, Tumor antigen BJ-HCC-15, FLJ20105, DNA excision repair protein ERCC-6-like, ATP-dependent helicase ERCC6-like, PLK1-interacting checkpoint helicase

SwissProt ID

A6QQR4 (Bovin), Q2NKX8 (Human), Q8BHK9 (Mouse)

Gene ID

54821 (ERCC6L), 236930 (Ercc6l)

Available reactivities

Hu (Human), Eq (Equine), Rb (Rabbit), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Immunoprecipitation (IP), Paraffin Sections (P)

Background of ERCC6L antibody

PICH (Plk1-interacting checkpoint helicase), also known as DNA excision repair protein ERCC-6-like (ERCC6L) or tumor antigen BJ-HCC-15, is a 1,250 amino acid protein belonging to the SNF2/RAD54 helicase family. PICH is a DNA helicase and an essential component of the spindle assembly checkpoint. During mitosis, PICH recruits MAD2 to kinetochores and also regulates the tension on centromic chromatin. PICH is concentrated in between the kinetochores in prometophase cells, while in metaphase it localizes to the thin threads composed of catenated centromeric DNA that stretch between sister kinetochores. PICH is phosphorylated by Plk, which prevents PICH from associating with chromosome arms and restricts the localization of PICH to the kinetochore-centromere region. PICH/Plk interaction is also required for correct Plk localization to the kinetochore. PICH contains one helicase ATP-binding domain, two TPR repeats and one helicase C-terminal domain.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ERCC6L antibody

  Rabbit Polyclonal Anti-ERCC6L Antibody - N-terminal region  
WB Suggested Anti-ERCC6L Antibody Titration: 0.2-1 ug/ml; Positive Control: THP-1 cell lysate Rabbit IgG Purified Eq, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

ERCC6L antibody

  Rabbit Polyclonal Anti-ERCC6L Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using (ERCC6L Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200) Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

ERCC6L - human gene knockout kit via CRISPR

ERCC6L - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ERCC6L - human gene knockout kit via CRISPR

ERCC6L - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ERCC6L - human gene knockout kit via CRISPR

ERCC6L - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ERCC6L - human gene knockout kit via CRISPR

ERCC6L - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ercc6l - mouse gene knockout kit via CRISPR

Ercc6l - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Ercc6l - mouse gene knockout kit via CRISPR

Ercc6l - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ercc6l - mouse gene knockout kit via CRISPR

Ercc6l - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ercc6l - mouse gene knockout kit via CRISPR

Ercc6l - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ERCC6L overexpression lysate

ERCC6L overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ercc6l (GFP-tagged) - Mouse excision repair cross-complementing rodent repair deficiency complementation group 6 - like (Ercc6l), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ercc6l (GFP-tagged) - Mouse excision repair cross-complementing rodent repair deficiency complementation group 6 - like (Ercc6l), 200 uL, >10^7 TU/mL  
200 µl / €2,100.00
  OriGene Technologies, Inc.

Lenti ORF particles, Ercc6l (Myc-DDK-tagged) - Mouse excision repair cross-complementing rodent repair deficiency complementation group 6 - like (Ercc6l), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ercc6l (Myc-DDK-tagged) - Mouse excision repair cross-complementing rodent repair deficiency complementation group 6 - like (Ercc6l), 200 uL, >10^7 TU/mL  
200 µl / €1,890.00
  OriGene Technologies, Inc.

13 Item(s)

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