ERN2 / IRE2 antibody

Principal name

ERN2 / IRE2 antibody

Alternative names for ERN2 / IRE2 antibody

Inositol-requiring protein 2, Ire1-beta, Serine/threonine-protein kinase/endoribonuclease IRE2, Endoplasmic reticulum-to-nucleus signaling 2

SwissProt ID

Q76MJ5 (Human), Q9Z2E3 (Mouse)

Gene ID

10595 (ERN2)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of ERN2 / IRE2 antibody

The accumulation of unfolded proteins within the endoplasmic recticulum (ER) of yeast and mammalian cells activates the unfolded protein response (UPR) pathway and leads to the transcription of ER-specific genes involved in protein folding. The activation of the UPR requires the ER transmembrane kinase IRE1p (for inositol-requiring and ER-to-nucleus signaling protein). IRE1α and IRE1β are two mammalian homologs of the yeast IRE1p. These related proteins localize to the ER lumen and contain both a short transmembrane domain that spans the ER membrane and a cytosolic Ser/Thr kinase domain. IRE1 activation involves the oligomerization and trans-phosphorylation of the cytosolic portion of the proteins, which then potentiates its intrinsic kinase activity and, in turn, stimulates transcription of UPR-targeted genes.

General readings

Iwawaki, T. et al., Nat. Cell Biol. 3(2): 158-164 (2001)
Niwa, M. et al., Cell 99(7): 691-702 (1999)
Wang, X.Z. et al., EMBO J. 17(19): 5708-5717 (1998)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ERN2 / IRE2 antibody

  Rabbit Polyclonal Anti-ERN2 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (ERN2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ERN2 / IRE2 (N-term) antibody

Western blot analysis of ERN2 (arrow) in mouse stomach tissue lysates (35ug/lane) using ERN2 / IRE2 antibody Cat.-No. AP13752PU-N (N-term). Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ERN2 / IRE2 (C-term) antibody

The anti-ERN2 Pab is used in Western blot to detect ERN2 in mouse liver tissue lysate Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ERN2 / IRE2 antibody

ERN2 / IRE2 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

ERN2 / IRE2 antibody

ERN2 / IRE2 Rabbit Hu E
0.4 ml / €390.00
  Abnova Taiwan Corp.

ERN2 / IRE2 antibody

ERN2 / IRE2 Rabbit Hu E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

ERN2 / IRE2 antibody

ERN2 / IRE2 Goat Hu E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

ERN2 / IRE2 antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ERN2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P
50 µg / €230.00
  Assay Biotech

ERN2 / IRE2 antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ERN2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P
0.1 mg / €330.00
  Assay Biotech

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ERN2 (mGFP-tagged) - Human endoplasmic reticulum to nucleus signaling 2 (ERN2), 200 uL, >10^7 TU/mL

Lenti ORF particles, ERN2 (mGFP-tagged) - Human endoplasmic reticulum to nucleus signaling 2 (ERN2), 200 uL, >10^7 TU/mL  
200 µl / €2,010.00
  OriGene Technologies, Inc.

Lenti ORF particles, ERN2 (Myc-DDK tagged) - Human endoplasmic reticulum to nucleus signaling 2 (ERN2) , 200 uL, >10^7 TU/mL

Lenti ORF particles, ERN2 (Myc-DDK tagged) - Human endoplasmic reticulum to nucleus signaling 2 (ERN2) , 200 uL, >10^7 TU/mL  
200 µl / €1,810.00
  OriGene Technologies, Inc.

11 Item(s)

per page
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