ERP1 antibody

Principal name

ERP1 antibody

Alternative names for ERP1 antibody

Effector cell peptidase receptor 1, BIRC5OS

SwissProt ID

Q14868 (Human)

Gene ID

8475

Ncbi ID

9606

Available reactivities

Hu (Human)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of ERP1 antibody

Cellular receptors for blood proteases regulate chemotaxis, extracellular proteolysis, and growth behavior of normal and malignant cells. Effector cell protease receptor-1 (EPR1) is a receptor for the coagulation protease factor Xa. EPR1 is characterized by a cysteine-rich extracellular module, a single membrane-spanning domain, and a serine-rich cytoplasmic tail featuring at least 15 potential phosphorylation sites. EPR1 also contains 2 N-linked glycosylation sites, 4 O-linked glycosylation sites, and a chondroitin sulfate attachment site, which may provide anchoring for carbohydrate chains, EPR1 transfectants bind to factor Xa in a specific and saturable manner, and in the absence of factor V/Va promote prothrombin activation in a factor Xa concentration-dependent reaction. Activated platelets and megakaryocytes express EPR1. Both EPR1 and membrane-bound factor Va are thought to be required to mediate factor Xa binding to the activated platelet to form a functional prothrombinase complex.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ERP1 (C-term) antibody

The anti-EPR1 C-term Pab is used in Western blot to detect EPR1 in HL60 cell lysate. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ERP1 antibody

The EPR1 polyclonal antibody ( Cat # PAB4710 ) is used in Western blot to detect EPR1 in HL-60 cell lysate. Rabbit IgG Purified Hu E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

2 Item(s)

per page
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