ERVFRDE1 / HERV-FRD antibody

Principal name

ERVFRDE1 / HERV-FRD antibody

Alternative names for ERVFRDE1 / HERV-FRD antibody

Envelope polyprotein, Syncytin-2, HERV-FRD_6p24.1 provirus ancestral Env polyprotein

SwissProt ID

P60508 (Human)

Gene ID

405754 (ERVFRD-1)

Available reactivities

Hu (Human)

Available hosts


Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of ERVFRDE1 / HERV-FRD antibody

Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their origil function during evolution. This endogenous envelope protein has retained its origil fusogenic properties. HERV-FRD can make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity.Human endogenous retroviruses (HERVs) make up approximately 8% of the human genome. Although most HERVs are nonfunctiol, the HERV-W (ERVWE1; MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors.

General readings

Vargas, A., et al. J. Mol. Biol. 392(2):301-318(2009)
Chen, C.P., et al. Biol. Reprod. 79(5):815-823(2008)
Malassine, A., et al. Retrovirology 5, 6 (2008)
Mangeney, M., et al. Proc. Natl. Acad. Sci. U.S.A. 104(51):20534-20539(2007)
Malassine, A., et al. Placenta 28 (2-3), 185-191 (2007)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ERVFRDE1 / HERV-FRD antibody

WB Suggested Anti-HERV-FRD Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: HT1080 cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

ERVFRDE1 / HERV-FRD (N-term) antibody

Western blot analysis of ERVFRDE1 / HERV-FRD Antibody (N-term) Cat.-No AP52032PU-N in NCI-H460 cell line lysates (35ug/lane). This demonstrates the HERV-FRD antibody detected the HERV-FRD protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ERVFRDE1 / HERV-FRD antibody

Human HT1080; WB Suggested Anti-HERV-FRD Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: HT1080 cell lysate; HERV-FRD antibody - N-terminal region (ARP56008_P050) in Human HT1080 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

ERVFRDE1 / HERV-FRD antibody

ERVFRDE1 / HERV-FRD Rabbit IgG Aff - Purified Hu WB
0.1 mg / €340.00
  Novus Biologicals Inc.

ERVFRDE1 / HERV-FRD antibody

ERVFRDE1 / HERV-FRD Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

ERVFRDE1 / HERV-FRD antibody

Immunohistochemistry-Paraffin: ERVFRD-1 Antibody [NBP1-84837] Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in islet cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  


2 µg / €300.00
  Abnova Taiwan Corp.

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