ESAM antibody

Principal name

ESAM antibody

Alternative names for ESAM antibody

Endothelial cell-selective adhesion molecule

SwissProt ID

Q6AYD4 (Rat), Q925F2 (Mouse), Q96AP7 (Human)

Gene ID

90952 (ESAM), 69524 (Esam), 300519

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of ESAM antibody

Endothelial cellselective adhesion molecule (ESAM) is a 55 kDa type I transmembrane glycoprotein that belongs to the JAM family of immunoglobulin superfamily molecules. Human ESAM is synthesized as a 390 amino acid (aa) protein composed of a 29 aa signal peptide, a 216 aa extracellular region, a putative 26 aa transmembrane segment, and a 119 aa cytoplasmic domain. The extracellular region contains one V-type and one C2-type Ig domain and is involved in hemophilic adhesion. In the cytoplasmic domain, there is a docking site for the multifunctional adaptor protein MAGI1. The extracellular region of human ESAM shows 90%, 74%, 69% and 67% aa identity with monkey, canine, mouse and rat extracellular ESAM, respectively. ESAM is expressed on endothelial cells, activated platelets and megakaryocytes, and can be found associated with cell to cell junctions. Whether ESAM is restricted to a particular junctional type is not clear. ESAM deficient mice have no defect in vascularization but do have reduced angiogenic potential. This may be due to a decreased migratory response to FGF2.
Soluble ESAM is fused to a C-terminal His-tag (6x His).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ESAM antibody

Immunofluorescence staining of vascular endothelial cells from human foreskin (cryo-section of unfixed tissue) using anti-human ESAM Antibody Cat,.-No AP26026PU (green/red). Specimen provided by Prof. Dr. J. Wilting and Dr. K. Buttler, Goettingen. Rabbit Aff - Purified Hu ICC/IF, WB
0.2 mg / €370.00
  Acris Antibodies GmbH

ESAM antibody

Immunofluorescence staining of vascular endothelial cells from human foreskin (cryo-section of unfixed tissue) using anti-human ESAM Antibody Cat,.-No AP26026PU (green/red). Specimen provided by Prof. Dr. J. Wilting and Dr. K. Buttler, Goettingen. Rabbit Aff - Purified Hu ICC/IF, WB
0.1 mg / €270.00
  Acris Antibodies GmbH

ESAM antibody

ESAM Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

ESAM - human gene knockout kit via CRISPR

ESAM - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ESAM - human gene knockout kit via CRISPR

ESAM - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ESAM - human gene knockout kit via CRISPR

ESAM - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ESAM - human gene knockout kit via CRISPR

ESAM - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Esam - mouse gene knockout kit via CRISPR

Esam - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Esam - mouse gene knockout kit via CRISPR

Esam - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Esam - mouse gene knockout kit via CRISPR

Esam - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Esam - mouse gene knockout kit via CRISPR

Esam - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ESAM

  Recombinant protein of human endothelial cell adhesion molecule (ESAM)  
ESAM Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

ESAM

  Recombinant protein of human endothelial cell adhesion molecule (ESAM)  
ESAM Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €399.00
  OriGene Technologies, Inc.

ESAM

  Purified recombinant protein of Human endothelial cell adhesion molecule (ESAM)  
ESAM Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

ESAM (His-tag)

SDS-PAGE analysis of recombinant human ESAM. Sample was loaded in 15% SDS-polyacrylamide gel under reducing conditions and stained with Coomassie blue. Human Purified > 95 % by SDS-PAGE and silver stain E. coli
20 µg / €200.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

ESAM overexpression lysate

ESAM overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ESAM (mGFP-tagged) - Human endothelial cell adhesion molecule (ESAM), 200 uL, >10^7 TU/mL

Lenti ORF particles, ESAM (mGFP-tagged) - Human endothelial cell adhesion molecule (ESAM), 200 uL, >10^7 TU/mL  
200 µl / €970.00
  OriGene Technologies, Inc.

Lenti ORF particles, ESAM (Myc-DDK tagged) - Human endothelial cell adhesion molecule (ESAM) , 200 uL, >10^7 TU/mL

Lenti ORF particles, ESAM (Myc-DDK tagged) - Human endothelial cell adhesion molecule (ESAM) , 200 uL, >10^7 TU/mL  
200 µl / €870.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Esam (GFP-tagged ORF) - Rat endothelial cell adhesion molecule (Esam), 200 uL, >10^7 TU/mL

Lenti ORF particles, Esam (GFP-tagged ORF) - Rat endothelial cell adhesion molecule (Esam), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Esam (Myc-DDK-tagged ORF) - Rat endothelial cell adhesion molecule (Esam), 200 uL, >10^7 TU/mL

Lenti ORF particles, Esam (Myc-DDK-tagged ORF) - Rat endothelial cell adhesion molecule (Esam), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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