ETHE1 / HSCO antibody

Principal name

ETHE1 / HSCO antibody

Alternative names for ETHE1 / HSCO antibody

Ethylmalonic encephalopathy protein 1, Hepatoma subtracted clone one protein

SwissProt ID

O95571 (Human), Q3T094 (Bovin), Q9DCM0 (Mouse)

Gene ID

23474 (ETHE1), 4423474 (groEL)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of ETHE1 / HSCO antibody

Probably plays an important role in metabolic homeostasis in mitochondria. May function as a nuclear-cytoplasmic shuttling protein that binds transcription factor RELA/NFKB3 in the nucleus and exports it to the cytoplasm. Suppresses p53-induced apoptosis by preventing nuclear localization of RELA.Involvement in disease:Defects in ETHE1 are a cause of ethylmalonic encephalopathy (EE) . EE is an autosomal recessive disorder characterized by neurodevelopmental delay and regression, recurrent petechiae, acrocyanosis, diarrhea, leading to death in the first decade of life. It is also associated with persistent lactic acidemia and ethylmalonic and methylsuccinic aciduria.

General readings

Tiranti V. et al. (2009) Nat Med. 15:200-205.Mineri R. et al. (2008) J Med Genet. 45:473-478

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ETHE1 / HSCO antibody

Immunoperoxidase of purified MaxPab antibody to ETHE1 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml] Mouse Purified Hu E(detection), ICC/IF, P, WB
50 µg / €370.00
  Abnova Taiwan Corp.

ETHE1 / HSCO antibody

WB Suggested Anti-ETHE1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: COLO205 cell lysateETHE1 is supported by BioGPS gene expression data to be expressed in COLO205 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

ETHE1 / HSCO antibody

Western blot analysis of ETHE1 antibody (Center) (AP17350PU-N) in mouse kidney tissue lysates (35 µg/lane). ETHE1 (arrow) was detected using the purified Pab. Rabbit Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ETHE1 / HSCO (C-term) antibody

Western blot analysis of ETHE1 antibody (C-term) (AP17351PU-N) in mouse liver tissue lysates (35 µg/lane). ETHE1 (arrow) was detected using the purified Pab. Rabbit Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ETHE1 / HSCO antibody

ETHE1 / HSCO Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

ETHE1 / HSCO antibody

Immunohistochemistry-Paraffin: ETHE1 Antibody [NBP1-81688] - Immunohistochemical staining of human rectum shows strong cytoplasmic positivity(granular pattern) in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

ETHE1 / HSCO antibody

Immunohistochemistry-Paraffin: ETHE1 Antibody [NBP1-81689] - Immunohistochemical staining of human rectum shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

ETHE1 / HSCO antibody

Immunohistochemistry-Paraffin: ETHE1 Antibody [NBP1-81690] - Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ETHE1 / HSCO

ETHE1 / HSCO Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

ETHE1 / HSCO (13-254, His-tag)

ETHE1 / HSCO Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €940.00
  Acris Antibodies GmbH

ETHE1 / HSCO (13-254, His-tag)

ETHE1 / HSCO Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €370.00
  Acris Antibodies GmbH

ETHE1 / HSCO

ETHE1 / HSCO Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

ETHE1 / HSCO

ETHE1 / HSCO Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

ETHE1 / HSCO

ETHE1 / HSCO Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

ETHE1 / HSCO

ETHE1 / HSCO Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ETHE1 293T Cell Transient Overexpression Lysate(Denatured)

ETHE1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

ETHE1 overexpression lysate

ETHE1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

17 Item(s)

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