ETS2 antibody

Principal name

ETS2 antibody

Alternative names for ETS2 antibody

Protein C-ets-2

SwissProt ID

A1A4L6 (Bovin), P10157 (Chick), P15036 (Human), P15037 (Mouse)

Gene ID

2114 (ETS2), 23872 (Ets2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Dros (Drosophila), Ze (Zebrafish), Eq (Equine), Rb (Rabbit), GP (Guinea Pig), Gt (Goat), Por (Porcine), Sh (Sheep)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of ETS2 antibody

ETS2 contains an ETS DNA-binding domain and belongs to the ETS family. ETS2 is a target of protein kinase C and upregulates GM-CSF. Ets2 and its targets play essential roles in endothelial cell function. Coexpression of Ets-2 and SRC-1 significantly associated with the rate of recurrence and HER expression in breast cancer. Overexpression of ETS2 is associated with human esophageal squamous cell carcinoma. ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Zabuawala, T., et al. Cancer Res. 70(4):1323-1333(2010)
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Shalaby, A.A., et al. Mod. Pathol. 22(8):996-1005(2009)
Sutter, W., et al. J Craniomaxillofac Surg 37(5):263-271(2009)
Staun-Ram, E., et al. Reprod. Biol. Endocrinol. 7, 135 (2009)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ETS2 antibody

  ETS2 mouse monoclonal antibody, clone OTI2A3 (formerly 2A3)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-ETS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA505391) Mouse IgG1 OTI2A3 Purified Hu ICC/IF, P, WB
0.1 ml / €350.00
  OriGene Technologies, Inc.


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