Exonuclease 1 (EXO1) antibody

Principal name

Exonuclease 1 (EXO1) antibody

Alternative names for Exonuclease 1 (EXO1) antibody

Exonuclease I, EXOI, HEX1

SwissProt ID

Q9QZ11 (Mouse), Q9UQ84 (Human)

Gene ID

9156 (EXO1), 26909 (Exo1)

Available reactivities

Hu (Human), Pl (Plant), Ms (Mouse)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ChIP assay (ChIP)

Background of Exonuclease 1 (EXO1) antibody

Comparative evaluation of the expression patterns of the human and mouse genes, combined with previous biochemical and yeast genetic studies, indicate that the Exo1 (Exonuclease I) proteins are important contributors to chromosome processing during mammalian DNA repair and recombination. In mice, the mExo1 gene maps to distal chromosome 1, consistent with the recent mapping of the orthologous human HEX1/ hEXO1 gene to chromosome 1q42-q43. mExo1 is expressed prominently in testis, an area of active homologous recombination, and spleen, a prominent lymphoid tissue. In both mammalian and yeast systems, Exo1 is a 5'-3' double stranded DNA exonuclease that has previously been implicated in DNA mismatch repair (MMR). The mismatch repair (MMR) system ensures genome integrity by removing mispaired and unpaired bases that originate during replication. In humans, Exo1 interacts with MSH2 and MLH1 and has been proposed to be a redundant exonuclease in MM. In both mammalian and yeast systems, Exo1 plays a structural role in MMR and stabilizes multiprotein complexes containing a number of MMR proteins.

General readings

Kim JC, Roh SA, Yoon YS, Kim HC, Park IJ.
MLH3 and EXO1 alterations in familial colorectal cancer patients not fulfilling Amsterdam criteria.
Cancer Genet Cytogenet. 2007 Jul 15;176(2):172-4. No abstract available.
PMID: 17656264

Items 1 to 20 of 22 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Exonuclease 1 (EXO1) antibody

  Goat Polyclonal Antibody against EXO1  
TA303326 (0.2µg/ml) staining of A549 cell lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Exonuclease 1 (EXO1) (N-term) antibody

Western blot analysis of anti-EXO1 Antibody (N-term) (Cat.#AP12539PU-N) in NCI-H460 cell line lysates (35ug/lane). EXO1 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Exonuclease 1 (EXO1) antibody

Western blot (WB) analysis of Exo1 antibody (Cat.-No.: AP20554PU-N) in extracts from raw264.7 cells. Rabbit Aff - Purified Hu, Ms ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Exonuclease 1 (EXO1) antibody

IHC Image of AP22963PU-N
Skeletal muscle, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Purified Hu P
50 µg / €470.00
  Acris Antibodies GmbH

Exonuclease 1 (EXO1) antibody

Immunofluorescence analysis of A549 cells, using EXO1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

Exonuclease 1 (EXO1) antibody

Immunofluorescence analysis of A549 cells, using EXO1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

EXO1 - human gene knockout kit via CRISPR

EXO1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

EXO1 - human gene knockout kit via CRISPR

EXO1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

EXO1 - human gene knockout kit via CRISPR

EXO1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Exo1 - mouse gene knockout kit via CRISPR

Exo1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Exo1 - mouse gene knockout kit via CRISPR

Exo1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Exo1 - mouse gene knockout kit via CRISPR

Exo1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Exo1 - mouse gene knockout kit via CRISPR

Exo1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

EXO1 overexpression lysate

EXO1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, EXO1 (mGFP-tagged) - Human exonuclease 1 (EXO1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, EXO1 (mGFP-tagged) - Human exonuclease 1 (EXO1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, EXO1 (mGFP-tagged) - Human exonuclease 1 (EXO1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, EXO1 (mGFP-tagged) - Human exonuclease 1 (EXO1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, EXO1 (mGFP-tagged)-Human exonuclease 1 (EXO1), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, EXO1 (mGFP-tagged)-Human exonuclease 1 (EXO1), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, EXO1 (Myc-DDK tagged) - Human exonuclease 1 (EXO1), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, EXO1 (Myc-DDK tagged) - Human exonuclease 1 (EXO1), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, EXO1 (Myc-DDK tagged) - Human exonuclease 1 (EXO1), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, EXO1 (Myc-DDK tagged) - Human exonuclease 1 (EXO1), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, EXO1 (Myc-DDK-tagged)-Human exonuclease 1 (EXO1), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, EXO1 (Myc-DDK-tagged)-Human exonuclease 1 (EXO1), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Items 1 to 20 of 22 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn