EXOSC10 antibody

Principal name

EXOSC10 antibody

Alternative names for EXOSC10 antibody

Exosome component 10, PMSCL, PMSCL2, RRP6, Autoantigen PM/Scl 2, P100 polymyositis-scleroderma overlap syndrome-associated autoantigen, Polymyositis/scleroderma autoantigen 100 kDa, PM/Scl-100, Polymyositis/scleroderma autoantigen 2

SwissProt ID

P56960 (Mouse), Q01780 (Human)

Gene ID

5394 (EXOSC10)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat), African clawed frog, Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of EXOSC10 antibody

The exosome is a multi-subunit complex composed of several highly conserved proteins, some of which are 3’ to 5’ exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3’ region. EXOSC10, also known as PMSCL, PMSCL2, p2, p3, p4, RRP6, Rrp6p, PM-Scl, or PM/Scl-100, is an 885 amino acid protein that contains one HRDC domain and one 3’-5’ enonuclease domain. Localized to both the cytoplasm and the nucleus, EXOSC10 is part of the post-splicing exosome complex and is involved in mRNA surveillance, mRNA nuclear export and nonsense-mediated decay of mRNAs containing premature stop codons. against EXOSC10 have been found in patients with scleroderma and/or polymyositis (chronic diseases of the skin and muscle, respectively), suggesting that EXOSC10 may be involved in the pathogenesis of these diseases. Two isoforms of EXOSC10 exist due to alternative splicing events.

General readings

Lehner,B. (2004) Genome Res. 14 (7), 1315-1323

9 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EXOSC10 antibody

WB Suggested Anti-EXOSC10 Antibody Titration: 5.0 ug/ml; ELISA Titer: 1: 62500; Positive Control: Jurkat cell lysate.EXOSC10 is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EXOSC10 antibody

WB Suggested Anti-EXOSC10 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Transfected 293T Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

EXOSC10 antibody

Detection limit for recombinant GST tagged EXOSC10 is approximately 1ng/ml as a capture antibody. Mouse IgG2a 1E6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

EXOSC10 antibody

Human Intestine; Rabbit Anti-EXOSC10 Antibody. Catalog Number: ARP40225. Paraffin Embedded Tissue: Human Intestine. Cellular Data: Epithelial cells of intestinal villas. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; EXOSC10 antibody - C-terminal region (ARP40225_T100) in Human Intestine cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Hu, Ms, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

EXOSC10 antibody

Human 293T; Host:Rabbit. Target Name:EXOSC10. Sample Tissue:Human 293T. Antibody Dilution: 1.0ug/ml. EXOSC10 is supported by BioGPS gene expression data to be expressed in HEK293T.; EXOSC10 antibody C-terminal region (ARP40227_P050) in Human 293T cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

EXOSC10

EXOSC10 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

EXOSC10

EXOSC10 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

EXOSC10

EXOSC10 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

EXOSC10 overexpression lysate

EXOSC10 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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