EXOSC6 / MTR3 antibody

Principal name

EXOSC6 / MTR3 antibody

Alternative names for EXOSC6 / MTR3 antibody

Exosome component 6, p11, Exosome complex exonuclease MTR3, mRNA transport regulator 3 homolog

SwissProt ID

Q5RKV6 (Human), Q8BTW3 (Mouse)

Gene ID

118460 (EXOSC6), 72544 (Exosc6)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Por (Porcine)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of EXOSC6 / MTR3 antibody

EXOSC6 constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.

General readings

Raijmakers,R., (2002) J. Mol. Biol. 323 (4), 653-663

9 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EXOSC6 / MTR3 antibody

  Rabbit Polyclonal Anti-EXOSC6 Antibody  
WB Suggested Anti-EXOSC6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Hu, Ms, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

EXOSC6 / MTR3 antibody

  Rabbit Polyclonal Anti-EXOSC6 Antibody  
WB Suggested Anti-EXOSC6 Antibody Titration: 5.0 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Hu, Ms, Por, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

EXOSC6 - human gene knockout kit via CRISPR

EXOSC6 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

EXOSC6 - human gene knockout kit via CRISPR

EXOSC6 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

EXOSC6 - human gene knockout kit via CRISPR

EXOSC6 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

EXOSC6 - human gene knockout kit via CRISPR

EXOSC6 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

EXOSC6 overexpression lysate

EXOSC6 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Exosc6 (GFP-tagged) - Mouse exosome component 6 (Exosc6), 200 uL, >10^7 TU/mL

Lenti ORF particles, Exosc6 (GFP-tagged) - Mouse exosome component 6 (Exosc6), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Exosc6 (Myc-DDK-tagged) - Mouse exosome component 6 (Exosc6), 200 uL, >10^7 TU/mL

Lenti ORF particles, Exosc6 (Myc-DDK-tagged) - Mouse exosome component 6 (Exosc6), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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