EXOSC6 / MTR3 antibody

Principal name

EXOSC6 / MTR3 antibody

Alternative names for EXOSC6 / MTR3 antibody

Exosome component 6, p11, Exosome complex exonuclease MTR3, mRNA transport regulator 3 homolog

SwissProt ID

Q5RKV6 (Human), Q8BTW3 (Mouse)

Gene ID

118460 (EXOSC6)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Por (Porcine)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C)

Background of EXOSC6 / MTR3 antibody

EXOSC6 constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.

General readings

Raijmakers,R., (2002) J. Mol. Biol. 323 (4), 653-663

9 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EXOSC6 / MTR3 antibody

WB Suggested Anti-EXOSC6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Hu, Ms, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

EXOSC6 / MTR3 antibody

WB Suggested Anti-EXOSC6 Antibody Titration: 5.0 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Hu, Ms, Por, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EXOSC6 / MTR3 antibody

Human Jurkat; WB Suggested Anti-EXOSC6 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Jurkat cell lysate; EXOSC6 antibody - N-terminal region (ARP41086_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

EXOSC6 / MTR3 antibody

Human Liver; Rabbit Anti-EXOSC6 Antibody. Catalog Number: ARP41087. Paraffin Embedded Tissue: Human Liver. Cellular Data: Hepatocytes. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; EXOSC6 antibody - N-terminal region (ARP41087_T100) in Human Liver cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

EXOSC6 / MTR3 antibody

EXOSC6 / MTR3 Rabbit Aff - Purified Can, Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

EXOSC6 / MTR3 antibody

Western Blot: Exosome component 6 Antibody [NBP1-57508] - This  antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 5ug/ml. Rabbit Purified Can, Hu P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

EXOSC6 / MTR3

EXOSC6 / MTR3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

EXOSC6 / MTR3

EXOSC6 / MTR3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

EXOSC6 overexpression lysate

EXOSC6 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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