EXOSC9 antibody

Principal name

EXOSC9 antibody

Alternative names for EXOSC9 antibody

EXOSC-9, PMSCL1, Exosome complex exonuclease RRP45, Exosome component 9, Autoantigen PM/Scl 1, PM/Scl-75, Polymyositis/scleroderma autoantigen 1, Polymyositis/scleroderma autoantigen 75 kDa, P75 polymyositis-scleroderma overlap syndrome-associated autoantigen

SwissProt ID

Q06265 (Human), Q3SWZ4 (Bovin), Q4QR75 (Rat), Q9JHI7 (Mouse)

Gene ID

5393 (EXOSC9)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse)

Available hosts

Goat, Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of EXOSC9 antibody

Exosome component 9 is part of the 3' -> 5' exoribonuclease complex that helps to degrade unstable mRNA. It binds to ARE-containing RNAs and performs 3' end trimming and degradation. These activities lead toward the maturation of RNA into more stable forms, which then become involved in transcription and translation. In the related Arabidopsis equivalent, loss of function of this protein is a lethal mutation. In ruminants, EXOSC9 is differentially expressed throughout the gut at different stages of development. EXOSC9 seems to be important in the degradation of histone mRNA and may be important in some downstream epigenetic effects.

General readings

Schilders G, Raijmakers R, Malmegrim KC, Vande Walle L, Saelens X, Vree Egberts W, van Venrooij WJ, Vandenabeele P, Pruijn GJ.
Caspase-mediated cleavage of the exosome subunit PM/Scl-75 during apoptosis. Arthritis Res Ther. 2007;9(1):R12.
PMID: 17280603

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EXOSC9 (C-term) antibody

TA305894 (0.3ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EXOSC9 antibody

Western Blot: Exosome Component 9 Antibody - WB analysis of EXOSC9 in A. HepG2 cell lysate and B. MCF7 cell lysate. Rabbit Purified Hu, Ms C, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

EXOSC9 antibody

Western Blot: PMSCL1 Antibody [NBP1-28490]-(0.3ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer). Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

EXOSC9 antibody

EXOSC9 Rabbit Aff - Purified Bov, Hu, Ms ICC/IF, P, WB
25 µl / €160.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

EXOSC9 (transcript variant 1)

EXOSC9 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

EXOSC9

EXOSC9 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

EXOSC9

EXOSC9 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

EXOSC9 overexpression lysate

EXOSC9 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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