Factor XIII B chain / F13B antibody

Principal name

Factor XIII B chain / F13B antibody

Alternative names for Factor XIII B chain / F13B antibody

Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain

SwissProt ID

P05160 (Human), Q07968 (Mouse)

Gene ID

2165 (F13B)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of Factor XIII B chain / F13B antibody

F13B contains 10 Sushi (CCP/SCR) domains. The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin. Defects in F13B can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.This gene encodes coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Pruissen,D.M., (2008) Blood 111 (3), 1282-1286

11 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Factor XIII B chain / F13B antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY F13B (RC219609, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-F13B. Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Factor XIII B chain / F13B antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY F13B (RC219609, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-F13B. Mouse IgG1 OTI1A3 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Factor XIII B chain / F13B antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY F13B (RC219609, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-F13B. Mouse IgG1 OTI2H10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Factor XIII B chain / F13B antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY F13B (RC219609, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-F13B. Mouse IgG1 OTI2D4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Factor XIII B chain / F13B antibody

Human HeLa; WB Suggested Anti-F13B Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Hela cell lysate; F13B antibody - middle region (ARP41999_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Factor XIII B chain / F13B antibody

Western blot analysis of Factor XIII B expression in HEK293T (A); NIH3T3 (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms ICC/IF, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Factor XIII B chain / F13B antibody

Western blot analysis of Factor XIII B expression in HEK293T (A); NIH3T3 (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms ICC/IF, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Factor XIII B chain / F13B antibody

Western blot analysis of Factor XIII B expression in HEK293T (A); NIH3T3 (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms ICC/IF, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Factor XIII B chain / F13B antibody

Western Blot: factor XIII Antibody [NBP1-58011] - This Anti-F13B antibody was used in Western Blot of PANC1     tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Factor XIII B chain / F13B antibody

Western Blot: factor XIII Antibody [NBP1-58012] - This Anti-F13B antibody was used in Western Blot of Hela tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

F13B overexpression lysate

F13B overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

11 Item(s)

per page
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