FAIM2 antibody

Principal name

FAIM2 antibody

Alternative names for FAIM2 antibody

Protein lifeguard, KIAA0950, LFG, TMBIM2, Fas apoptotic inhibitory molecule 2, Transmembrane BAX inhibitor motif-containing protein 2

SwissProt ID

O88407 (Rat), Q1LZ71 (Bovin), Q8K097 (Mouse), Q9BWQ8 (Human)

Gene ID

23017 (FAIM2), 72393 (Faim2), 246274

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Chk (Chicken), Hst (Hamster), Mky (Monkey), Op (Opossum), Bov (Bovine), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of FAIM2 antibody

Programmed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. FAIM2 is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-alpha death signal. In this respect, FAIM2 is functionally similar to the anti-apoptotic proteins FAIM, FLIP and Bcl-xL. FAIM2, a seven membrane spanning protein, can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas. FAIM2 is widely distributed, but highly expressed in the hippocampus and other neural tissues. FAIM2 was also identified as the neural membrane protein 35 (NMP35) and its expression is known to be regulated by the Phosphatidylinositol 3-kinase-Akt/PKB pathway.

General readings

1. "LFG: an anti-apoptotic gene that provides protection from fas-mediated cell death."
Somia N.V., Schmitt M.J., Vetter D.E., Van Antwerp D., Heinemann S.F., Verma I.M. Proc. Natl. Acad. Sci. U.S.A. 96:12667-12672(1999).
2. "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
Nagase T., Ishikawa K., Suyama M., Kikuno R., Hirosawa M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O. DNA Res. 6:63-70(1999).
3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team Genome Res. 14:2121-2127(2004).

16 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FAIM2 antibody

  Rabbit Polyclonal LFG Antibody  
Western blot analysis of LFG in EL4 cell lysate with LFG antibody at (A) 0.5 and (B) 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FAIM2 antibody

  FAIM2 / LIFEGUARD Rabbit Polyclonal (N-Terminus) Antibody  
FAIM2 Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €400.00
  OriGene Technologies, Inc.

FAIM2 antibody

  Rabbit Polyclonal Anti-FAIM2 Antibody  
Host: Rabbit; Target Name: FAIM2; Sample Tissue: HepG2 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

FAIM2 (1-50) antibody

Brain, cerebellum: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Can, Chk, Hu, Mky, Ms, Op, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

FAIM2 (Center) antibody

Western blot analysis of FAIM2 Antibody (Center) Cat.-No AP51511PU-N in U251 cell line lysates (35ug/lane). This demonstrates the FAIM2 antibody detected the FAIM2 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Faim2 - mouse gene knockout kit via CRISPR

Faim2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Faim2 - mouse gene knockout kit via CRISPR

Faim2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Faim2 - mouse gene knockout kit via CRISPR

Faim2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Faim2 - mouse gene knockout kit via CRISPR

Faim2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FAIM2

  Recombinant protein of human Fas apoptotic inhibitory molecule 2 (FAIM2)  
FAIM2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, FAIM2 (mGFP-tagged) - Human Fas apoptotic inhibitory molecule 2 (FAIM2), 200 uL, >10^7 TU/mL

Lenti ORF particles, FAIM2 (mGFP-tagged) - Human Fas apoptotic inhibitory molecule 2 (FAIM2), 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, FAIM2 (Myc-DDK tagged) - Human Fas apoptotic inhibitory molecule 2 (FAIM2) , 200 uL, >10^7 TU/mL

Lenti ORF particles, FAIM2 (Myc-DDK tagged) - Human Fas apoptotic inhibitory molecule 2 (FAIM2) , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Faim2 (GFP-tagged) - Mouse Fas apoptotic inhibitory molecule 2 (Faim2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Faim2 (GFP-tagged) - Mouse Fas apoptotic inhibitory molecule 2 (Faim2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Faim2 (Myc-DDK-tagged) - Mouse Fas apoptotic inhibitory molecule 2 (Faim2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Faim2 (Myc-DDK-tagged) - Mouse Fas apoptotic inhibitory molecule 2 (Faim2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Faim2 (GFP-tagged ORF) - Rat Fas apoptotic inhibitory molecule 2 (Faim2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Faim2 (GFP-tagged ORF) - Rat Fas apoptotic inhibitory molecule 2 (Faim2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Faim2 (Myc-DDK-tagged ORF) - Rat Fas apoptotic inhibitory molecule 2 (Faim2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Faim2 (Myc-DDK-tagged ORF) - Rat Fas apoptotic inhibitory molecule 2 (Faim2), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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