FAIM3 / TOSO antibody

Principal name

FAIM3 / TOSO antibody

Alternative names for FAIM3 / TOSO antibody

Fas apoptotic inhibitory molecule 3, Regulator of Fas-induced apoptosis Toso

SwissProt ID

A1KXC4 (Mouse), O60667 (Human), Q5M871 (Rat)

Gene ID

9214 (FAIM3), 69169 (Faim3), 548326

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of FAIM3 / TOSO antibody

Apoptosis is an important process in maintaining normal tissue homeostasis and function. One of the major signals that regulate this process is mediated by the activation of the Fas receptor by its ligand. This leads to the formation of a Fas associated death domain (FADD), containing death inducing signalling complex, and the activation of caspase-8, which in turn activates downstream effector caspases, such as caspase-3 and -7 (Curting and Cotter, 2003). Recent experiments have shown that overexpression of FAIM3, a novel regulator of Fas induced apoptosis in lymphoid cells, Jurkat cells and in transgenic mice renders these cells resistant to Fas induced apoptosis but not to TRAIL induced apoptosis (Hitoshi et al, 1998; Song and Jacob, 2005). Furthermore, FAIM3 was found to associate with FADD, suggesting that it functions by disrupting the formation of the death inducing signalling complex. Despite its predicted molecular weight, FAIM3 often migrates at 60 kDa in SDS PAGE.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FAIM3 / TOSO antibody

  Rabbit Polyclonal Toso Antibody  
Western blot analysis of Toso in human lung tissue lysate with Toso antibody at 1 µg/ml in either the (A) presence, or (B) absence of blocking peptide. Rabbit IgG Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FAIM3 / TOSO antibody

  FAIM3 mouse monoclonal antibody, clone OTI1E6 (formerly 1E6)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-FAIM3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA507395) Mouse IgG1 OTI1E6 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

FAIM3 / TOSO (C-term) antibody

Western blot analysis of Human lung lysate probed with Rabbit anti Human TOSO Antibody Cat.-No AP05598PU-N Rabbit IgG Purified Hu WB
0.1 mg / €330.00
  Acris Antibodies GmbH

FAIM3 / TOSO (C-term) antibody

Western blot analysis of Human lung lysate probed with Rabbit anti Human TOSO Antibody Cat.-No AP05598PU-N Rabbit IgG Purified Hu WB
50 µg / €270.00
  Acris Antibodies GmbH

FAIM3 / TOSO antibody

Kidney: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

FAIM3 - human gene knockout kit via CRISPR

FAIM3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

FAIM3 - human gene knockout kit via CRISPR

FAIM3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

FAIM3 - human gene knockout kit via CRISPR

FAIM3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

FAIM3 - human gene knockout kit via CRISPR

FAIM3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Faim3 - mouse gene knockout kit via CRISPR

Faim3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Faim3 - mouse gene knockout kit via CRISPR

Faim3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Faim3 - mouse gene knockout kit via CRISPR

Faim3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Faim3 - mouse gene knockout kit via CRISPR

Faim3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

FAIM3 overexpression lysate

FAIM3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

FAIM3 overexpression lysate

FAIM3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, FAIM3 (mGFP-tagged) - Human Fas apoptotic inhibitory molecule 3 (FAIM3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, FAIM3 (mGFP-tagged) - Human Fas apoptotic inhibitory molecule 3 (FAIM3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, FAIM3 (mGFP-tagged) - Human Fas apoptotic inhibitory molecule 3 (FAIM3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, FAIM3 (mGFP-tagged) - Human Fas apoptotic inhibitory molecule 3 (FAIM3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, FAIM3 (Myc-DDK tagged) - Human Fas apoptotic inhibitory molecule 3 (FAIM3), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, FAIM3 (Myc-DDK tagged) - Human Fas apoptotic inhibitory molecule 3 (FAIM3), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, FAIM3 (Myc-DDK tagged) - Human Fas apoptotic inhibitory molecule 3 (FAIM3), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, FAIM3 (Myc-DDK tagged) - Human Fas apoptotic inhibitory molecule 3 (FAIM3), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Faim3 (GFP-tagged) - Mouse Fas apoptotic inhibitory molecule 3 (Faim3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Faim3 (GFP-tagged) - Mouse Fas apoptotic inhibitory molecule 3 (Faim3), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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