FAK2 / PTK2B antibody

Principal name

FAK2 / PTK2B antibody

Alternative names for FAK2 / PTK2B antibody

PYK2, RAFTK, Protein tyrosine kinase 2 beta, Focal adhesion kinase 2, CAK-beta, CADTK, Proline-rich tyrosine kinase 2, Cell adhesion kinase beta, Calcium-dependent tyrosine kinase, Related adhesion focal tyrosine kinase

SwissProt ID

P70600 (Rat), Q14289 (Human), Q9QVP9 (Mouse)

Gene ID

2185 (PTK2B), 50646 (Ptk2b)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Mky (Monkey)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), EPair for Elisa (EPair)

Background of FAK2 / PTK2B antibody

Protein tyrosine kinase 2 beta, also known as PTK2B, PKB, PTK, CAKB, FAK2, FRNK. Entrez Protein NP_004094. It is a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

General readings

Ling,S., et al., (2004) Am. J. Physiol., Cell Physiol. 287 (3), C698-C706

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FAK2 / PTK2B antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between PTK2B and YES1 Huh7 cells were stained with anti-PTK2B rabbit purified polyclonal 1:1200 and anti-YES1 mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Rabbit Purified Hu, Rt E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

FAK2 / PTK2B antibody

Western blot analysis of extracts from 3T3 cells, using PYK2 (Ab-579) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FAK2 / PTK2B antibody

Western blot analysis of extracts from 3T3 cells, using PYK2 (Phospho-Tyr579) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FAK2 / PTK2B antibody

Predicted band size: 116 kDa . Positive control: 293 cells untreated or treated with Serum lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1: 293 cells untreated with Serum lysate Lane2: 293 cells r treated with Serum lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FAK2 / PTK2B antibody

Predicted band size: 116 kDa . Positive control: 293 cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1: 293 cells lysate Lane2: Treated with the peptide Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FAK2 / PTK2B antibody

Western blot analysis of extracts from 293 cells, using Phospho-PTK2B-Y402 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

FAK2 / PTK2B pTyr402 antibody

Transactivation of PYK2 Whole cell lysates of serum starved HepG2 tumor cells (20.000 cells per lane) were applied to SDS-PAGE and transferred to PVDF membranes. Immunoblots were probed with mab PYK2-14F6 (0.5 µg/ ml) for 1h at RT and developed by ECL (exp. time: 30 sec). lane 1:Co; lane 2: serum; lane 3: EGF; lane 4: H2O2;lane 5: Anisomycin; lane 6: Sorbit; lane 7: Arsen; lane 8:Ceramide. Mouse IgG1 14F6 Purified Hu, Ms, Rt E, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

FAK2 / PTK2B antibody

Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using PYK2 antibody Cat.-No AM06233SU-N Mouse IgG2a 5E2D5 Ascites Hu E, P, WB
0.1 ml / €440.00
  Acris Antibodies GmbH

FAK2 / PTK2B pTyr402 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using Pyk2 pTyr402 antibody AP02475PU. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €320.00
  Acris Antibodies GmbH

FAK2 / PTK2B pTyr402 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using Pyk2 pTyr402 antibody AP02475PU. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
50 µl / €240.00
  Acris Antibodies GmbH

FAK2 / PTK2B antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using Pyk2 antibody AP02719PU. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €270.00
  Acris Antibodies GmbH

FAK2 / PTK2B antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using Pyk2 antibody AP02719PU. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
50 µl / €230.00
  Acris Antibodies GmbH

FAK2 / PTK2B antibody

Immunohistochemistry (IHC) analyzes of PYK2 antibody (Cat.-No.: AP06298PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

FAK2 / PTK2B antibody

Immunohistochemistry (IHC) analyzes of PYK2 antibody (Cat.-No.: AP06408PU-N) in paraffin-embedded human brain colon carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

FAK2 / PTK2B (N-term) antibody

Kidney: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms P, WB
50 µl / €470.00
  Acris Antibodies GmbH

FAK2 / PTK2B antibody

Human Colon, MALT: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt E, P
50 µg / €470.00
  Acris Antibodies GmbH

FAK2 / PTK2B pTyr579 antibody

Immunohistochemical analysis of paraffin-embedded human brain tissue using PYK2 (Phospho-Tyr579) antibody AP55794PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €340.00
  Acris Antibodies GmbH

FAK2 / PTK2B pTyr579 antibody

Immunohistochemical analysis of paraffin-embedded human brain tissue using PYK2 (Phospho-Tyr579) antibody AP55794PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µl / €270.00
  Acris Antibodies GmbH

FAK2 / PTK2B antibody

PTK2B MaxPab polyclonal antibody. Western Blot analysis of PTK2B expression in rat brain. Mouse Serum Hu, Rt E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

FAK2 / PTK2B antibody

PTK2B MaxPab polyclonal antibody. Western Blot analysis of PTK2B expression in rat brain. Mouse Purified Hu, Rt E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

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