FAM193B antibody

Principal name

FAM193B antibody

Alternative names for FAM193B antibody

IRIZIO, KIAA1931

Gene ID

54540 (FAM193B)

Available reactivities

Hu (Human)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of FAM193B antibody

FAM193B Antibody: FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression ebled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.

General readings

Picchione F, Pritchard C, Lagutina I, et al. IRIZIO: a novel gene cooperating with PAX3-FOXO1 in alveolar rhabdomyosarcoma (ARMS). Carcinogenesis 2011; 32:452-62.
Linardic CM. PAX3-FOXO1 fusion gene in rhabdomyosarcoma. Cancer Lett. 2008; 270:10-8.

3 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FAM193B (N-term) antibody

Western blot analysis of FAM193B in Jurkat cell lysate with FAM193B antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FAM193B (N-term) Control Peptide

Western blot analysis of FAM193B in Jurkat cell lysate with FAM193B antibody Cat.-No. AP55508PU-N at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide (Cat.-No. AP55508CP-N).
50 µg / €160.00
  Acris Antibodies GmbH

FAM193B antibody

FAM193B Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

3 Item(s)

per page
  • LinkedIn