FAM59A antibody

Principal name

FAM59A antibody

Alternative names for FAM59A antibody


SwissProt ID

Q3UFT3, Q6NRE4, Q7ZVU1, Q9H706

Gene ID

64762 (FAM59A)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts


Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of FAM59A antibody

FAM59A, also known as GAREM, was initially identified through a mass spectroscoptic method that measures different phosphotyrosine states of proteins in response to different cell stimuli. FAM59A is a downstream molecule in the EGF signaling pathway that is tyrosine-phosphorylated, and this phosphorylation is needed for the binding of Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. ERK activation in response to EGF stimulation is regulated by FAM59A in COS-7 and HeLa cells, and the overexpression of FAM59A stimulated cell proliferation and colony formation in soft agar, suggesting that FAM59A might be a critical protein with roles in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FAM59A antibody

FAM59A Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
  OriGene Technologies, Inc.

FAM59A (C-term) antibody

FAM59A Rabbit Hu, Ms, Rt E, P, WB
  Acris Antibodies GmbH

FAM59A Control Peptide

  Acris Antibodies GmbH

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