FANCD2 antibody

Principal name

FANCD2 antibody

Alternative names for FANCD2 antibody

Fanconi anemia group D2 protein, FACD2, FACD

SwissProt ID

Q6IV68 (Rat), Q80V62 (Mouse), Q9BXW9 (Human)

Gene ID

2177 (FANCD2)

Available reactivities

Hu (Human), Mky (Monkey), Ms (Mouse), Rt (Rat), Prim (Primate)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), ChIP assay (ChIP), Frozen Sections (C)

Background of FANCD2 antibody

Fanconi Anemia Complementation Group D2 (FANCD2) protein is one of at least six factors shown to be involved in the autosomal-recessive cancer-prone disorder, Fanconi Anemia (FA). FA group D has been shown to be comprised of two separate proteins, FANCD1 and FANCD2. Mutations in BRCA2 can cause FANCD1. FANCD2 has been shown to colocalize with BRCA1 in ionizing radiation-induced foci. FANCD2 is involved in genomic resistance to DNA cross-linking reagents, and the arrest of DNA synthesis following exposure to ionizing radiation. FANCD2 has been shown to directly interact with NBS1.
FANCD2 is one of at least four different genes, of which when mutated can cause the Fanconi anemia phenotype characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomcyin C. FANCD2 is phosphorylated by ATM following ionizing radiation and this phosphorylation is required for activation of an S-phase checkpoint. It is also monoubiquitinated in response to DNA damage. It is postulated that FANCD2 may have a role in the cellular response to stalled replication forks or in the repair of replication-associated double-strand breaks.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FANCD2 antibody

Western Blot: FANCD2 Antibody [TA336272] - Analysis of FANCD2 in human PD20 cells. Image courtesy of anonymous customer review Rabbit Purified Hu, Ms, Prim C, ICC/IF, IP, P, WB
50 µl / €325.00
  OriGene Technologies, Inc.

FANCD2 antibody

Simple Western: FANCD2 Antibody [TA336730] - Simple Western lane view shows a specific band detected for FANCD2 in HeLa lysate.  This experiment was performed under reducing conditions using the Wes or Sally Sue separation system 12-230kDa (or 66-440kDa). Rabbit Purified Hu C, ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FANCD2 antibody

Staining of human prostate, glandular epithelium using FANCD2 polyclonal antibody ( Cat # PAB12428 ). Rabbit Hu, Ms C, ICC/IF, IP, WB
50 µl / €470.00
  Abnova Taiwan Corp.

FANCD2 antibody

Staining of human prostate, glandular epithelium using NB100-182. Rabbit HRP Hu, Ms ICC/IF, IP, P, WB
50 µl / €260.00
  Novus Biologicals Inc.

FANCD2 antibody

Western Blot: FANCD2 Antibody (FI-17) - Expression of FancD2 (mAb) in different cell lines. Proliferating cells were treated with 10-Gy IR. Fifty microgram protein was loaded each lane. Working dilution - 1:1000 LCL 6% SDS-PAGE. Mouse FI-17 Purified Hu IP, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FANCD2 antibody

Western blot analysis of extracts from JK cells, using FANCD2 (Ab-691) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FANCD2 antibody

Predicted band size: 166 kDa . Positive control: HL-60 cell lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FANCD2 antibody

Western blot analysis of FANCD2 expression in CalyculinA treated HT29 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FANCD2 antibody

Western blot analysis of extracts of various cell lines, using FANCD2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

FANCD2 antibody

Western Blot: FANCD2 [p Ser222] Antibody [TA336310] - FA-D2 fibroblasts were stably transfected with either pMMP (empty vector, A), FANCD2 (wt, B), FANCD2 (S222A, C), FANCD2 (triple mutant, D), or FANCD2 (quadruple mutant, E). Rabbit Purified Hu WB
0.2 ml / €379.00
  OriGene Technologies, Inc.

FANCD2 antibody

ELISA: FANCD2 Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

FANCD2 antibody

Formalin-Fixed Paraffin-Embedded Human Liver stained with FANCD2 antibody AM06065PU-N at 2.5 µg/ml followed by biotinylated anti-mouse IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Mouse IgG 103 Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

FANCD2 antibody

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG 6 Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

FANCD2 antibody

Immunohistochemical analysis in paraffin-embedded human breast carcinoma tissue using FANCD2  antibody (Cat.-No. AP06115PU-N). Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

FANCD2 pSer222 antibody

Western blot analysis of extracts from HT29 cells treated with CalyculinA using Phospho-FANCD2 (Ser222) antibody AP55916PU-N.The lane on the right is treated with the antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €340.00
  Acris Antibodies GmbH

FANCD2 pSer222 antibody

Western blot analysis of extracts from HT29 cells treated with CalyculinA using Phospho-FANCD2 (Ser222) antibody AP55916PU-N.The lane on the right is treated with the antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µl / €270.00
  Acris Antibodies GmbH

FANCD2 antibody

FANCD2 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

FANCD2 antibody

Expression of FancD2 ( mAb ) in different cell lines : proliferating cells were treated with IR or kept as mock of IR. Eight hours after IR, local proteins were isolated for Western blot analysis. Fifty microgram protein was loaded each lane. Working dilution of FANCD2 monoclonal antibody, clone FI-17 ( Cat # MAB2398 ) is 1 : 1000. Lane1 : U2OS, Lane2 : U2OS+IR, Lane3 and 4 : MEF, Lane5 : MO59K+IR, Lane6 : SiHa+IR. Mouse FI-17 Hu IP, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

FANCD2 pSer222 antibody

FA-D2 fibroblasts were stably transfected with either pMMP ( empty vector, A ), FANCD2 ( wt, B ), FANCD2 ( S222A, C ), FANCD2 ( triple mutant, D ), or FANCD2 ( quadruple mutant, E ). Cells were irradiated with 15 Gy ( + ), and whole cell lysates were immunoblotted with either anti-FANCD2 or Phospho-FANCD2 S222 polyclonal antibody, ( Cat # PAB12530 ). Rabbit Hu WB
0.2 ml / €560.00
  Abnova Taiwan Corp.

FANCD2 pSer222 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using FANCD2 (Phospho-Ser222) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €205.00
  Assay Biotech

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