FANCM antibody

Principal name

FANCM antibody

Alternative names for FANCM antibody

Fanconi anemia group M protein, FACM, KIAA1596, Protein Hef ortholog, FAAP250, ATP-dependent RNA helicase FANCM, Fanconi anemia-associated polypeptide of 250 kDa

SwissProt ID

Q8BGE5 (Mouse), Q8IYD8 (Human)

Gene ID

57697 (FANCM)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of FANCM antibody

Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromosomal instability. At the cellular level, FA is characterized by spontaneous chromosomal breakage and a unique hypersensitivity to DNA cross-linking agents. The thirteen FA proteins that have been characterized are important for regulating chromosomal stability and genome surveillance. Eight of these proteins, namely FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL and FANCM, comprise the FA core complex, which catalyzes a key reaction in DNA repair: the monoubiquitination of FANCD2. FANCM (Fanconi anemia, complementation group M) is a member of the DEAD-box helicase family of proteins and contains a DEAH helicase domain and a nuclease domain. Localizing to chromatin fractions, FANCM is phosphorylated in a cell cycle-dependent manner and is believed to function as an anchor, recruiting the FA core complex to chromatin. Mutations in the gene encoding FANCM can lead to Fanconi anemia.

6 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FANCM antibody

Detection of FANCM in 293 EBN4 cell lysates  using anti-FANCM. Rabbit Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FANCM antibody

Immunofluorescence of purified MaxPab antibody to FANCM on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

FANCM antibody

Western blot analysis of FANCM in 293 EBN4 cell lysates using FANCM polyclonal antibody ( Cat # PAB12529 ). Rabbit Hu WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

FANCM antibody

FANCM Rabbit Aff - Purified Hu WB
25 µl / €140.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FANCM

FANCM Human
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

FANCM 293T Cell Transient Overexpression Lysate(Denatured)

FANCM 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

6 Item(s)

per page
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