FAT1 antibody

Principal name

FAT1 antibody

Alternative names for FAT1 antibody

Protocadherin Fat 1, CDHF7, FAT, Cadherin family member 7, Cadherin-related tumor suppressor homolog, Protein fat homolog

SwissProt ID

O13735 (Schpo), P38225 (Yeast), Q14517 (Human)

Gene ID

2195 (FAT1)

Available reactivities

Dros (Drosophila), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of FAT1 antibody

This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq].

General readings

General / background references:Bryant PJ et al. Mutations at the fat locus interfere with cell proliferation control and epithelial morphogenesis in Drosophila. Dev Biol 129:541-54 (1988). PubMed PMID: 3417051

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FAT1 antibody

  Anti-FAT1 Rabbit Polyclonal Antibody  
Predicted band size: 50 kDa . Positive control: Recombinant protein . Recommended dilution: 1/ 2000-5000. (Gel: 10%SDS-PAGE Protein: 2 ug Primary antibody: 1/2000 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

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