Fatty acid synthase antibody

Principal name

Fatty acid synthase antibody

Alternative names for Fatty acid synthase antibody

FASN, FAS

SwissProt ID

P07855 (Rabit), P12276 (Chick), P12785 (Rat), P19096 (Mouse), P49327 (Human), Q71SP7 (Bovin)

Gene ID

14104 (Fasn), 2194 (FASN)

Available reactivities

Chk (Chicken), Hu (Human), Mky (Monkey), Ms (Mouse), Por (Porcine), Rt (Rat), Hst (Hamster), Prim (Primate)

Available hosts

Rabbit, Mouse, Goat

Available applications

Paraffin Sections (P), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Frozen Sections (C), EPair for Elisa (EPair), Flow Cytometry (F)

Background of Fatty acid synthase antibody

Fatty acid synthetase (FASN) is a key player of fatty acid biosynthetic pathway and it catalyzes formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and DPH (de novo lipid synthesis). Localized in cytoplasm and melanosomes, FASN is expressed at low level in normal adult tissues; however, it is significantly upregulated in cancer cells. The FASN expression is regulated by growth factors/growth factor receptors (EGFR and HER2) and steroid hormone /steroid hormone receptors (ER, AR and progesterone receptor). Downstream of the receptors, PI3K-AKT and MAPK sigling mediate FASN expression through SREBP-1c. FASN expression is also controlled by p53 family proteins and SPOT14, lipogenesis-related nuclear protein generally overexpressed in breast cancer. Extracellular stresses including hypoxia and low pH also induce the FASN expression in cancer cells and USP2a stabilises FASN alongwith promotion of its mTOR-dependent selective translatiol induction. FASN activation provides rapidly proliferating tumor cells sufficient amount of lipids for membrane biogenesis and confers growth/survival advantage possibly acting as a metabolic oncogene. Because FASN-inhibitors are selectively toxic to tumor cells, it has emerged as an attractive target for cancer.

  1. Quick-Filters:
  2. Highly Validated (5)

Items 1 to 20 of 33 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Fatty acid synthase antibody

Fatty Acid Synthase antibody [N1], N-term detects FASN protein by Western blot analysis. A. 30 ug PC-12 whole cell lysate/extract. B. 30 ug Rat2 whole cell lysate/extract. 5 % SDS-PAGE. Fatty Acid Synthase antibody [N1], N-term (TA308750) dilution: 1:1000 Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Fatty acid synthase antibody

Sample (50 ug of whole cell lysate). A: mouse liver. 5% SDS PAGE. TA308751 diluted at 1:1000. Rabbit IgG Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Fatty acid synthase antibody

Western blot analysis of FASN Antibody (Center) (Cat. #TA324935) in Ramos cell line lysates (35ug/lane).FASN (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Fatty acid synthase antibody

Western Blot: Fatty Acid Synthase Antibody [TA336642] - Analysis of Fatty Acid Synthase, using TA336642. Samples: 50 ug of total mouse liver lysate. Rabbit Purified Chk, Hst, Hu, Ms, Por, Prim, Rt C, ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Fatty acid synthase antibody

Immunoperoxidase of monoclonal antibody to FASN on formalin-fixed paraffin-embedded human breast cancer tissue. [antibody concentration 10ug/ml] Mouse IgG1 3F2-1F3 Purified Hu E, ICC/IF, P, WB
50 µg / €370.00
  Abnova Taiwan Corp.

Fatty acid synthase antibody

FASN Antibody (Center) (Cat. #TA324351) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the FASN antibody detected the FASN protein (arrow). Mouse IgM 497CT15.2.5 Ascites Hu, Ms ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Fatty acid synthase antibody

FASN Antibody (Center) (Cat. #TA324352) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the FASN (Center) antibody detected the FASN (Center) protein (arrow). Mouse IgM 497CT15.2.5 Purified Hu, Ms ICC/IF, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Fatty acid synthase antibody

Human Prostate (formalin-fixed, paraffin-embedded) stained with FASN antibody AP22808PU-N followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Ig Fraction Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Fatty acid synthase (2118-2129) antibody

Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Fu, Gorilla, Hu P
50 µg / €470.00
  Acris Antibodies GmbH

Fatty acid synthase antibody

Immunofluorescence of purified MaxPab antibody to FASN on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

Fatty acid synthase antibody

Immunoprecipitation of FASN transfected lysate using anti-FASN MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with FASN MaxPab mouse polyclonal antibody (B01) (H00002194-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

Fatty acid synthase antibody

Western Blot analysis of FASN expression in transfected 293T cell line (H00002194-T01) by FASN MaxPab polyclonal antibody.

Lane 1: FASN transfected lysate(48.30 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Fatty acid synthase antibody

FASN monoclonal antibody (M01), clone 3F2-1F3 Western Blot analysis of FASN expression in 293 ( Cat # L026V1 ). Mouse IgG1 3F2-1F3 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

Fatty acid synthase antibody

Immunofluorescence of monoclonal antibody to FASN on HeLa cell . [antibody concentration 10 ug/ml] Mouse IgG1 3B3-1D6 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Fatty acid synthase antibody

Fatty acid synthase Mouse IgG1 3B3-1D6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Fatty acid synthase antibody

Western Blot analysis of FASN expression in transfected 293T cell line by FASN monoclonal antibody (M03), clone S1.

Lane 1: FASN transfected lysate(48.3 KDa).
Lane 2: Non-transfected lysate. Mouse IgG1 S1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Fatty acid synthase antibody

Detection limit for recombinant GST tagged FASN is approximately 0.3ng/ml as a capture antibody. Mouse IgG2a 3A2 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

Fatty acid synthase antibody

Western blot analysis of Fasn in tissue lysates ( brain, hypothalmus, and liver and muscle ) using Fasn polyclonal antibody ( Cat # PAB12142 ). Rabbit Chk, Hu, Ms, Rt C, IP, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

Fatty acid synthase antibody

Western blot analysis of FASN expression in MCF7 (A); U2OS (B); SKBR3 (C); HepG2 (D) whole cell lysates. Rabbit Aff - Purified Hu IP, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Fatty acid synthase antibody

Western blot analysis of FASN expression in MCF7 (A); U2OS (B); SKBR3 (C); HepG2 (D) whole cell lysates. Rabbit Aff - Purified Hu IP, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Items 1 to 20 of 33 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn