FBW1A antibody

Principal name

FBW1A antibody

Alternative names for FBW1A antibody

BTRC, BTRCP, FBXW1A, E3RSIkappaB, F-box/WD repeat-containing protein 1A, F-box and WD repeats protein beta-TrCP, pIkappaBalpha-E3 receptor subunit

SwissProt ID

Q9Y297 (Human)

Gene ID

8945 (BTRC)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Flow Cytometry (F)

Background of FBW1A antibody

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class; in addition to an F-box, this protein contains multiple WD-40 repeats. This protein is homologous to Xenopus bTrCP1, yeast Met30, Neurospora Scon2 and Drosophila Slimb proteins. It interacts with HIV-1 Vpu and connects CD4 to the proteolytic machinery. It also associates specifically with phosphorylated IkappaBalpha and beta-catenin destruction motifs, probably functioning in multiple transcriptional programs by activating the NF-kappaB pathway and inhibiting the beta-catenin pathway. [provided by RefSeq]. Transcript Variant: This variant (1) contains an additional 108 nt fragment within the coding region, as compared to variant 2, and thus encodes an in-frame 36 aa longer isoform than variant 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FBW1A antibody

Anti-BTRC mouse monoclonal antibody (TA502465) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BTRC(RC207025). Mouse IgG2b OTI2H2 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

FBW1A antibody

Predicted band size: 69 kDa . Positive control: Kidney tissue lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FBW1A antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BTRC (RC207025, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BTRC. Mouse IgG1 OTI1F10 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

FBW1A antibody

Anti-BTRC mouse monoclonal antibody (TA502464) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BTRC(RC207025). Mouse IgG1 OTI3D5 Purified Hu ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

FBW1A antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BTRC (RC207025, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BTRC. Mouse IgG1 OTI1D4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

FBW1A antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BTRC (RC207025, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BTRC. Mouse IgG1 OTI1F3 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

FBW1A antibody

Anti-BTRC mouse monoclonal antibody (TA502524) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BTRC(RC207025). Mouse IgG1 OTI1A4 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

FBW1A (N-term) antibody

BRTC1 Antibody (N-term) (Cat. #AP50409PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BRTC1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu ICC/IF, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

FBW1A antibody

FBW1A Rabbit Hu WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

FBW1A antibody

FBW1A Rabbit IgG Hu WB
0.1 mg / €420.00
  Novus Biologicals Inc.

10 Item(s)

per page
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