FBW1B antibody

Principal name

FBW1B antibody

Alternative names for FBW1B antibody

FBXW11, BTRCP2, FBXW1B, KIAA0696, beta-TrCP2, HOS, F-box/WD repeat-containing protein 11, F-box/WD repeat-containing protein 1B, F-box and WD repeats protein beta-TrCP2, Homologous to Slimb protein

SwissProt ID

Q9UKB1 (Human)

Gene ID

23291 (FBXW11)

Available reactivities

Hu (Human), Bov (Bovine), Chimp (Chimpanzee), Chk (Chicken), Ms (Mouse), Can (Canine), Ze (Zebrafish), Eq (Equine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of FBW1B antibody

FBXW11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.

General readings

Peschiaroli, A., et al. Oncogene 29(9):1384-1393(2010)
Lievens, S., et al. J. Proteome Res. 8(2):877-886(2009)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007)
Peschiaroli, A., et al. Mol. Cell 23(3):319-329(2006)
Sabile, A., et al. Mol. Cell. Biol. 26(16):5994-6004(2006).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FBW1B antibody

  Rabbit polyclonal Beta TrCP2 antibody  
WB using Anti-ßTrCP2 antibody shows detection of mouse and human ßTrCP2 (arrowhead) in NIH3T3 (lane 1) and 293 (lane 2) whole cell lysates.The primary antibody was used at1:200.  Detection occurred using HRP conjugated Goat-anti-Rabbit IgG diluted 1:20,000 in blocking buffer (p/n MB-070) for 1 h at 4 ?. Rabbit IgG Aff - Purified Bov, Can, Chimp, Chk, Eq, Hu, Ms E, WB
0.1 mg / €356.00
  OriGene Technologies, Inc.

FBW1B (Center) antibody

  Rabbit polyclonal FBXW11 Antibody (Center)  
FBXW11 Antibody (Center) (Cat. #TA324389) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the FBXW11 antibody detected the FBXW11 protein (arrow). Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

FBW1B antibody

  Rabbit Polyclonal Anti-FBXW11 Antibody  
FBW1B Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

FBW1B antibody

  Rabbit Polyclonal Anti-FBXW11 Antibody  
WB Suggested Anti-FBXW11 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: 293T cell lysateFBXW11 is supported by BioGPS gene expression data to be expressed in HEK293T Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

FBXW11 - human gene knockout kit via CRISPR

FBXW11 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

FBXW11 - human gene knockout kit via CRISPR

FBXW11 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

FBXW11 - human gene knockout kit via CRISPR

FBXW11 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FBW1B (transcript variant 2)

  Recombinant protein of human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 2  
FBW1B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

FBXW11 overexpression lysate

FBXW11 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

FBXW11 overexpression lysate

FBXW11 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

FBXW11 overexpression lysate

FBXW11 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

FBXW11 overexpression lysate

FBXW11 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, FBXW11 (mGFP-tagged) - Human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, FBXW11 (mGFP-tagged) - Human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,130.00
  OriGene Technologies, Inc.

Lenti ORF particles, FBXW11 (mGFP-tagged) - Human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, FBXW11 (mGFP-tagged) - Human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, FBXW11 (Myc-DDK tagged) - Human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, FBXW11 (Myc-DDK tagged) - Human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €1,010.00
  OriGene Technologies, Inc.

Lenti ORF particles, FBXW11 (Myc-DDK tagged) - Human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, FBXW11 (Myc-DDK tagged) - Human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

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