FBXO15 antibody

Principal name

FBXO15 antibody

Alternative names for FBXO15 antibody

F-box only protein 15, FBX15

SwissProt ID

Q3SYW0 (Bovin), Q8NCQ5 (Human), Q9QZN0 (Mouse)

Gene ID

201456 (FBXO15)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of FBXO15 antibody

FBXO15, also known as FBX15, is a 434 amino acid protein that contains one C-terminal F-box domain and belongs to the F-box family of proteins. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO15 can directly interact with Skp1 p19 and CUL-1. In addition, FBXO15 is a target of the transcription factor Oct-3/4, however, it does not appear to be essential for early development and fertility.

General readings

Lamesch, P., et al. Genomics 89(3):307-315(2007)
Jin, J., et al. Genes Dev. 18(21):2573-2580(2004)
Tokuzawa, Y., et al. Mol. Cell. Biol. 23(8):2699-2708(2003)
Winston, J.T., et al. Curr. Biol. 9(20):1180 (1999).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FBXO15 antibody

WB Suggested Anti-FBXO15 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: OVCAR-3 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

FBXO15 (N-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue reacted with FBXO15 Antibody (N-term) Cat.-No AP51624PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

FBXO15 antibody

Human 293T; FBXO15 antibody - N-terminal region (ARP53103_P050) validated by WB using 293T cells lysate at 1:500.; FBXO15 antibody - N-terminal region (ARP53103_P050) in Human 293T cells using Western Blot Rabbit Aff - Purified Bov, Hu, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

FBXO15 antibody

Western Blot: FBXO15 Antibody [NBP1-32860] - (30 ug of whole cell lysate) A: Raji 10% SDS PAGE diluted at 1:1000 Rabbit IgG Hu WB
0.1 mg / €420.00
  Novus Biologicals Inc.

FBXO15 antibody

Western Blot: FBXO15 Antibody [NBP1-56901] - This Anti-FBXO15 antibody was used in Western Blot of OVCAR-3     tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FBXO15

FBXO15 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

FBXO15

FBXO15 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

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