FBXO25 antibody

Principal name

FBXO25 antibody

Alternative names for FBXO25 antibody

F-box only protein 25, FBX25

SwissProt ID

Q1RMS8 (Bovin), Q641X7 (Rat), Q8TCJ0 (Human), Q9D2Y6 (Mouse)

Gene ID

26260 (FBXO25)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Por (Porcine), Rt (Rat), Ze (Zebrafish), African clawed frog

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C)

Background of FBXO25 antibody

FBXO25 is a member of the F box protein family which is characterized by an approximately 40 amino acid motif, the F box. The F box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1 cullin F box), which function in phosphorylation dependent ubiquitination. The F box proteins are divided into 3 classes: Fbws containing WD 40 domains, Fbls containing leucine rich repeats, and Fbxs containing either different protein protein interaction modules or no recognizable motifs. FBXO25 belongs to the Fbxs class. There are three named isoforms produced by alternative splicing.FBXO25, also known as FBX25, is a 367 amino acid protein that contains one C-terminal F-box domain and belongs to the Fbx class of the F-box family of proteins. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. Expressed at high levels in brain, FBXO25 localizes predominantly to the nucleus and directly interacts with Skp1 p19 and CUL-1. Disruption of the gene encoding FBXO25 can lead to X-linked mental retardation.

General readings

Hagens,O., (2006) Biochim. Biophys. Acta 1760 (1), 110-118

14 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FBXO25 antibody

WB Suggested Anti-FBXO25 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human heart Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

FBXO25 antibody

WB Suggested Anti-FBXO25 Antibody Titration: 1.25ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FBXO25 antibody

FBXO25 monoclonal antibody (M01), clone 2F1 Western Blot analysis of FBXO25 expression in COLO 320 HSR ( Cat # L020V1 ). Mouse IgG2a 2F1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

FBXO25 antibody

Human Heart; WB Suggested Anti-FBXO25 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human heart; FBXO25 antibody - N-terminal region (ARP43117_P050) in Human Heart cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Por, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

FBXO25 antibody

Human kidney; FBXO25 antibody - C-terminal region (ARP43118_T100) in Human kidney cells using Immunohistochemistry Rabbit Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Por, Rt, Ze P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

FBXO25 antibody

Western Blot: FBXO25 Antibody [NBP1-55044] - This Anti-FBXO25 antibody was used in Western Blot of Fetal Heart tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

FBXO25 antibody

Western Blot: FBXO25 Antibody [NBP1-55045] - This Anti-FBXO25 antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 1.25ug/ml. Rabbit Purified Can, Hu, Ze P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FBXO25 (full length, N-term HIS tag, transcript variant 3)

FBXO25 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

FBXO25

FBXO25 Human
2 µg / €300.00
  Abnova Taiwan Corp.

FBXO25

FBXO25 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

FBXO25

FBXO25 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

FBXO25 HEK293 Cell Transient Overexpression Lysate (Non-Denatured)

FBXO25 HEK293 Cell Transient Overexpression Lysate (Non-Denatured)  
0.1 mg / €270.00
  Abnova Taiwan Corp.

FBXO25 overexpression lysate

FBXO25 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

FBXO25 overexpression lysate

FBXO25 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

14 Item(s)

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