FBXO43 antibody

Principal name

FBXO43 antibody

Alternative names for FBXO43 antibody

F-box only protein 43, EMI2, FBP5B, Endogenous meiotic inhibitor 2

SwissProt ID

Q4G163 (Human), Q66H04 (Rat), Q8AXF4 (Xenla), Q8CDI2 (Mouse)

Gene ID

286151 (FBXO43), 100101275 (fbxo43)

Available reactivities

Hu (Human), Mky (Monkey), Chimp (Chimpanzee), Ms (Mouse), Bov (Bovine), Por (Porcine), Rt (Rat), Can (Canine), Xen (Xenopus), Ze (Zebrafish)

Available hosts

Rabbit, Mouse, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), Immunoprecipitation (IP)

Background of FBXO43 antibody

The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP) (1). IL-1RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NFkappa-B inducing kinae (NIK) and of NF-kappaB, recruits to the IL-1R complex through IL-1RAcP (2). IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP (3,4). Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.

General readings

1. DiDonato JA, Hayakawa M, Rothwarf DM, Zandi E, Karin M. A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB. Nature 1997;388:548-54
2. Regnier CH, Song HY, Gao X, Goeddel DV, Cao Z, Rothe M. Identification and characterization of an IkappaB kinase. Cell 1997;90:373-83
3. Zandi E, Rothwarf DM, Delhase M, Hayakawa M, Karin M. The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation. Cell 1997;91:243-52
Woronicz JD, Gao X, Cao Z, Rothe M, Goeddel DY. IkappaB kinase-alpha: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK. Science 1997;278:866-9

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FBXO43 antibody

Sample (30 ug of whole cell lysate). A: NIH-3T3. B: JC. 7.5% SDS PAGE. TA308747 diluted at 1:1000. Rabbit IgG Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FBXO43 (C-term) antibody

FBXO43 Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, F, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FBXO43 antibody

Western blot analysis of IL-1RAcP in HeLa whole cell lysate with IL-1RAcP antibody (C2) at 1:1000 dilution. Rabbit IgG Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FBXO43 antibody

Western blot analysis of IL-1RAcP in HeLa whole cell lysate with IL-1RAcP antibody at 1:500 dilution. Rabbit IgG Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FBXO43 antibody

WB using Anti-Fbp5B antibody. Panels A and B show two identical membranes containing marker, in vitro translated Fbp5b (Fbp5b ivt), and a whole cell extract from 293T cells loaded in duplicate). Panel A shows antibody reactivity. Panel B shows antibody reactivity after first pre-incubating the antibody with the immunizing peptide Peptide inhibition completely removes the in vitro translated band and greatly reduces the endogenous band from 293T cells. Rabbit IgG Aff - Purified Chimp, Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FBXO43 (N-term) antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Liver. Rabbit Aff - Purified Hu, Mky, Ms, Rt E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

FBXO43 Control Peptide

FBXO43 Purified
50 µg / €190.00
  Acris Antibodies GmbH

FBXO43 Control Peptide

FBXO43
50 µg / €160.00
  Acris Antibodies GmbH

FBXO43 Control Peptide

FBXO43
50 µg / €160.00
  Acris Antibodies GmbH

FBXO43 antibody

FBXO43 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

FBXO43 antibody

FBXO43 Mouse IgG2a 4B6 Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

FBXO43 antibody

Western blot using FBXO43 polyclonal antibody ( Cat # PAB10206 ).
Panels A and B show two identical membranes containing marker, in vitro translated FBXO43 ( FBXO43 ivt ), and a whole cell extract from 293T cells loaded in duplicate.
Panel A shows antibody reactivity.
Panel B shows antibody reactivity after first pre-incubating the antibody with the immunizing peptide.
This pre-incubation greatly diminishes specific band recognition.
Peptide inhibition completely removes the in vitro translated band and greatly reduces the endogenous band from 293T cells.
When this experiment was repeated using a mock in vitro translation, no band was detected ( data not shown ).
Personal Communication, Daniele Guardavaccaro, NYU Cancer Institute. Chimp, Hu
0.1 mg / €560.00
  Abnova Taiwan Corp.

FBXO43 antibody

Immunohistochemistry: F-box protein 43 Antibody [NBP1-31473] - Immunohistochemical analysis of paraffin-embedded Saos-2, using NBP1-31473 at 1:100 dilution. Rabbit IgG Hu ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

FBXO43 antibody

Immunohistochemistry-Paraffin: F-box protein 43 Antibody [NBP1-84708] - Immunohistochemical staining of human stomach shows distinct cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

FBXO43 antibody

Immunohistochemistry-Paraffin: F-box protein 43 Antibody [NBP1-84709] - Immunohistochemical staining of human kidney shows distinct cytoplasmic positivity in cells in tubules. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FBXO43

FBXO43 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

FBXO43

FBXO43 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

FBXO43 overexpression lysate

FBXO43 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

18 Item(s)

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