FBXW12 antibody

Principal name

FBXW12 antibody

Alternative names for FBXW12 antibody

FBW12, FBXO12, FBXO35, F-box only protein 35, F-box/WD repeat-containing protein 12, F-box and WD-40 domain-containing protein 12

SwissProt ID

Q6X9E4 (Human)

Gene ID

285231 (FBXW12)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P)

Background of FBXW12 antibody

Belonging to the F-box family of proteins, FBXO35 (F-box only protein 35), also designated F-box and WD-40 domain-containing protein 12 (FBXW12 or FBXO12), is a 464 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO35 can directly interact with Skp1 p19 and CUL-1. FBXO35 is ubiquitously expressed at low levels in most human tissues.

General readings

Jin, J., et al. Genes Dev. 18(21):2573-2580(2004)
Zeng, L., et al. Mol. Biol. Rep. 31(1):51-57(2004).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FBXW12 antibody

Host: Rabbit; Target Name: FBXW12; Sample Tissue: Fetal Brain lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

FBXW12 (C-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma reacted with FBXW12 Antibody (C-term) Cat.-No AP51636PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

FBXW12 antibody

FBXW12 Mouse IgG2a 1A9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FBXW12

FBXW12 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

FBXW12

FBXW12 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

FBXW12

FBXW12 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

FBXW12

FBXW12 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

FBXW12 293T Cell Transient Overexpression Lysate(Denatured)

FBXW12 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

FBXW12 overexpression lysate

FBXW12 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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