FBXW2 / FBW2 / FWD2 antibody
Principal name
FBXW2 / FBW2 / FWD2 antibody
Alternative names for FBXW2 / FBW2 / FWD2 antibody
F-box/WD repeat-containing protein 2, F-box and WD-40 domain-containing protein 2, Protein MD6
Gene ID
26190 (FBXW2)
Ncbi ID
9606, NP_036296, ABM86476.1, NM_012164, NP_036296.1, NP_036296.2
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)
Background of FBXW2 / FBW2 / FWD2 antibody
F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. FBXW2 is the second identified member of the F-box family and contains multiple WD-40 repeats.F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.
General readings
Winston JT, Koepp DM, Zhu C, Elledge SJ, Harper JW. A family of mammalian F-box proteins. Curr Biol. 1999 Oct 21;9(20):1180-2. PMID: 10531037
- Quick-Filters:
- Highly Validated (1)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA329817 | FBXW2 / FBW2 / FWD2 antibody |
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| Rabbit Polyclonal Anti-FBXW2 Antibody | |||||||
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Rabbit | IgG | Purified | Hu | WB |
50 µg /
€325.00
|
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| OriGene Technologies, Inc. | |||||||
 +4 additional images |
Highly validated antibody! |
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| TA302888 | FBXW2 / FBW2 / FWD2 (C-term) antibody |
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| Goat Polyclonal Antibody against FBXW2 | |||||||
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Goat | Aff - Purified | Bov, Can, Hu, Ms, Por, Rt | P, WB |
0.1 mg /
€325.00
|
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| OriGene Technologies, Inc. | |||||||
| +1 additional image |
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CRISPR
| Catalog No. | Species | Donor Vector | |
|---|---|---|---|
| KN205840 | FBXW2 - human gene knockout kit via CRISPR |
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Human | GFP-Puro |
1 kit /
€1,200.00
|
| OriGene Technologies, Inc. | |||
| KN205840BN | FBXW2 - human gene knockout kit via CRISPR |
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|
Human | mBFP-Neo |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN205840LP | FBXW2 - human gene knockout kit via CRISPR |
||
|
Human | Luciferase-Puro |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN205840RB | FBXW2 - human gene knockout kit via CRISPR |
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Human | RFP-BSD |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
Lysates
| Catalog No. | ||
|---|---|---|
| LY415943 | FBXW2 overexpression lysate |
|
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0.1 mg /
€280.00
|
|
| OriGene Technologies, Inc. |
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC205840L2V | Lenti ORF particles, FBXW2 (mGFP-tagged) - Human F-box and WD repeat domain containing 2 (FBXW2), 200 uL, >10^7 TU/mL |
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200 µl /
€1,050.00
|
|
| OriGene Technologies, Inc. | ||
