FBXW2 / FBW2 / FWD2 antibody

Principal name

FBXW2 / FBW2 / FWD2 antibody

Alternative names for FBXW2 / FBW2 / FWD2 antibody

F-box/WD repeat-containing protein 2, F-box and WD-40 domain-containing protein 2, Protein MD6

SwissProt ID

Q58D00 (Bovin), Q60584 (Mouse), Q9UKT8 (Human)

Gene ID

26190 (FBXW2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine), Chk (Chicken), Ze (Zebrafish), African clawed frog

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Dot blot (Dot)

Background of FBXW2 / FBW2 / FWD2 antibody

F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. FBXW2 is the second identified member of the F-box family and contains multiple WD-40 repeats.F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.

General readings

Winston JT, Koepp DM, Zhu C, Elledge SJ, Harper JW. A family of mammalian F-box proteins. Curr Biol. 1999 Oct 21;9(20):1180-2. PMID: 10531037

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  2. Highly Validated (2)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FBXW2 / FBW2 / FWD2 antibody

1Hum. Adult Placenta; Host: Rabbit; Target Name: CHAD; Sample Tissue: Human Adult Placenta; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

FBXW2 / FBW2 / FWD2 antibody

Hum. Adult Placenta; Host: Rabbit. Target Name: CHAD . Sample Tissue: Human Adult Placenta . Antibody Dilution: 1.0ug/ml.; FBXW2 antibody - middle region (ARP43109_P050) in Hum. Adult Placenta cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

FBXW2 / FBW2 / FWD2 (C-term) antibody

TA302888 staining (0.3µg/ml) of Human Kidney lysate (RIPA buffer, 30µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FBXW2 / FBW2 / FWD2 antibody

FBXW2 / FBW2 / FWD2 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

FBXW2 / FBW2 / FWD2 antibody

FBXW2 polyclonal antibody ( Cat # PAB6464 ) staining ( 3 µg/ml ) of paraffin embedded human kidney.  Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining. Goat Hu, Ms, Rt E, P, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

FBXW2 / FBW2 / FWD2 antibody

Western Blot: FBXW2 Antibody [NB100-1300] - NB100-1300 staining (0.3ug/ml) of Human Kidney lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

FBXW2 / FBW2 / FWD2 antibody

Western Blot: FbxW2 Antibody [NBP1-31019] - Western blot analysis of FbxW2 Antibody on: A:A431(GTX27909) 10% SDS PAGE Diluted at 1:1500 Rabbit IgG Hu Dot, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

FBXW2 / FBW2 / FWD2 antibody

Western Blot: FBXW2 Antibody [NBP1-55043] - This Anti-FBXW2 antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

FBXW2 overexpression lysate

FBXW2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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