FCGRT / FCRN antibody

Principal name

FCGRT / FCRN antibody

Alternative names for FCGRT / FCRN antibody

Neonatal Fc receptor, IgG receptor FcRn large subunit p51, IgG Fc fragment receptor transporter alpha chain

SwissProt ID

P13599 (Rat), P55899 (Human), Q61559 (Mouse)

Gene ID

2217 (FCGRT)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Por (Porcine), GP (Guinea Pig), Rt (Rat), Eq (Equine), Sh (Sheep)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of FCGRT / FCRN antibody

FcRN present in the intestinal epithelium of neonatal mice and rats mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn animals to acquire passive immunity. FcRn (also designated FCGRT, Brambell receptor, FcRn å chain, IgG Gc receptor and neonatal Fc-receptor) is comprised of a heavy chain and ∫-2-Microglobulin. FcRn heavy chain shows approximately 35% amino acid identity to an MHC class I molecule. FcRN localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal catabolism. This protection mechanism is a major constituent for ensuring IgG are the longest lived of all plasma proteins.

General readings

Cianga,P., (2007) Virchows Arch. 451 (4), 859-860

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FCGRT / FCRN antibody

WB Suggested Anti-FCGRT Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate.FCGRT is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

FCGRT / FCRN antibody

Human Lung Tissue; Rabbit Anti-FCGRT Antibody . Catalog Number: ARP46406_P050 . Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue . Observed Staining: Membrane and cytoplasmic in alveolar type I cells . Primary Antibody Concentration: 1:100 . Other Working Concentrations: 1/600 . Secondary Antibody: Donkey anti-Rabbit-Cy3 . Secondary Antibody Concentration: 1:200 . Magnification: 20X . Exposure Time: 0.5 - 2.0 sec .; Rabbit Anti-FCGRT Antibody (ARP46406_P050) ) in Human Lung Tissue using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms, Por WB
50 µg / €350.00
  AVIVA Systems Biology

FCGRT / FCRN antibody

Western Blot: FCGRT Antibody [NBP1-59061] - This Anti-FCGRT antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 0.5ug/ml. Rabbit Aff - Purified Bov, Can, Hu, Ms, Por WB
50 µg / €440.00
  Novus Biologicals Inc.

FCGRT / FCRN antibody

Immunohistochemistry-Paraffin: FCGRT Antibody [NBP1-89127] - Immunohistochemical staining of human liver shows positivity in a subset of cells in sinusoids. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

FCGRT / FCRN antibody

Immunohistochemistry-Paraffin: FCGRT Antibody [NBP1-89128] - Immunohistochemical staining of human liver shows positivity of a subset of cells in sinusoids. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FCGRT / FCRN (transcript variant 1)

FCGRT / FCRN Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

FCGRT / FCRN (transcript variant 2)

FCGRT / FCRN Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

FCGRT / FCRN (transcript variant 2)

FCGRT / FCRN Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

FCGRT / FCRN

FCGRT / FCRN Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

FCGRT / FCRN

FCGRT / FCRN Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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