FDCSP / C4orf7 antibody

Principal name

FDCSP / C4orf7 antibody

Alternative names for FDCSP / C4orf7 antibody

FDC secreted protein, FDC-SP, Follicular dendritic cell secreted peptide

SwissProt ID

Q8NFU4 (Human)

Gene ID

260436 (FDCSP)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of FDCSP / C4orf7 antibody

Follicular dendritic cells are cells that facilitate antigen recognition by B cells in follicles. This kind of dendritic cell is not bone marrow derived and is not a kind of blood cell. It is purely a resident of the follicles of secondary lymphoid organs. B cells form germinal centers around follicular dendritic cells in lymphoid organs. Dendritic cells form from monocytes, white blood cells which circulate in the body and, depending on the right signal, can turn into dendritic cells or macrophages. The monocytes in turn are formed from stem cells in the bone marrow.In normal tissue this antibody identifies dendritic cells and a proportion of B lymphocytes. Evidence in pathological tissue and functional studies suggests it binds to an epitope expressed by antigen presenting cells. Within the macrophage/dendritic cell populations the epitope seen by RFD1 is coexpressed with RFD7 by a subset of cells that exhibit suppressive activity on T cell stimulation.

General readings

Wang,C., et al. (2010) Oncol. Rep. 24 (4), 933-939Al-Alwan,M., et al. (2007) . Immunol. 178 (12), 7859-7867

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FDCSP / C4orf7 antibody

Immunohistochemistry: C4orf7 Antibody - Normal and malignant tissues were generally negative. A sub-population of cells in the salivary gland and surface epithelial cells of tonsil showed strong cytoplasmic positivity. Weak to moderate nuclear and/or cytoplasmic positivity was observed in many cases of ovarian and cervical cancers.  Image and statement courtesy of the Human Protein Atlas (HPA). Rabbit IgG Purified Hu E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

FDCSP / C4orf7 antibody

Immunohistochemistry: C4orf7 Antibody [20620002] - Normal and malignant tissues were generally negative. A sub-population of cells in the salivary gland and surface epithelial cells of tonsil showed strong cytoplasmic positivity. Weak to moderate nuclear and/or cytoplasmic positivity was observed in many cases of ovarian and cervical cancers.  Image and statement courtesy of the Human Protein Atlas (HPA). Rabbit Hu E, P
50 µg / €440.00
  Novus Biologicals Inc.

FDCSP / C4orf7 antibody

Immunohistochemistry-Paraffin: C4orf7 Antibody [NBP1-84702] Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in squamous epithelial cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FDCSP / C4orf7 (18-85, His-tag)

FDCSP / C4orf7 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

FDCSP / C4orf7 (18-85, His-tag)

FDCSP / C4orf7 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

5 Item(s)

per page
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