FER / TYK3 antibody

Principal name

FER / TYK3 antibody

Alternative names for FER / TYK3 antibody

c-FER, p94-FER, Tyrosine kinase 3, Proto-oncogene tyrosine-protein kinase FER

SwissProt ID

P09760 (Rat), P16591 (Human), P70451 (Mouse)

Gene ID

2241 (FER), 14158 (Fert2)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of FER / TYK3 antibody

FER (fer tyrosine kinase) is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases, which shares a functional domain and is involved in signaling pathways through receptor tyrosine kinases (RTK) and cytokine receptors. The Fes /Fps family is distinct from c-Src, c-Abl and related nRTKs and was originally distinguished as a homolog to retroviral oncoproteins. In vivo, Fer kinase assembles into homotrimers via conserved coiled-coil domains. The N-terminal coiled-coil domains of Fer can autophosphorylate in trans, thereby regulating their cellular function through differential phosphorylation states. Growth factor exposure can induce tyrosine phosphorylation of Fer and recruitment of Fer to RTK complexes containing p85. It is expressed predominantly in mature hematopoietic cells of the granulocytic and monocytic lineage, and has been shown to be expressed in vascular endothelial cells. Fer is implicated in insulin signaling, cell-cell signaling, human prostatic proliferative diseases, and is involved in the regulation of G1 progression.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FER / TYK3 antibody

  Rabbit polyclonal FER (Ab-402) antibody  
Western blot analysis of extracts from HeLa cells, treated with paclitaxel (1uM, 24hours), using FER (Ab-402) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FER / TYK3 antibody

  Rabbit polyclonal anti-FER antibody  
Western blot analysis of extracts from HeLa cells, using FER antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FER / TYK3 antibody

  Rabbit Polyclonal Fer Antibody  
Western Blot: FER Antibody [TA336745] - Jurkat cell lysates. Rabbit Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FER / TYK3 antibody

  Rabbit Polyclonal Anti-FER Antibody  
Western blot analysis on Jurkat cell lysate using FER Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FER / TYK3 (incl. pos. control) antibody

Detection of endogenous fer: Whole cell extracts of pervanadate (VH) treated tumor cells (20.000 cells per lane) were applied to SDS-PAGE and transferred to PVDF membranes. Immunoblots were probed with mab fer-6B9 (0.5 µg/ ml) for 1h at RT and developed by ECL (exp. time: 30 sec). VH treatment: 15 min. Lane 1: A431; Lane 2: SW480 lane 3: SW620; lane 4: HT29; lane 5: MCF-7; lane 6: MDA-MB231; lane 7: T47D Mouse IgG1 6B9 Purified Can, Hu, Ms, Rt E, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

FER / TYK3 antibody

Immunohistochemical analysis of paraffin-embedded human kidney tissues using FER antibody Cat.-No AM06187SU-N Mouse IgG1 5D2C4 Ascites Hu, Ms ICC/IF, P, WB
0.1 ml / €440.00
  Acris Antibodies GmbH

FER / TYK3 antibody

AM20530SU-N FER antibody staining of Formalin-Fixed, Paraffin-Embedded Human Kidney followed by biotinylated anti-mouse IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Mouse IgG1 5D2C4 Ascites Hu E, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

FER / TYK3 antibody

Western blot (WB) analysis of Fer Antibody (Cat.-No.: AP06672PU-N) in extracts from HeLa cells. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

FER / TYK3 (C-term) antibody

The anti-FER Pab is used in Western blot to detect FER in HL-60 cell lysate. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

FER / TYK3 pTyr402 antibody

Immunohistochemical analysis of paraffin-embedded human brain tissue using FER (Phospho-Tyr402) antibody AP55754PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms P, WB
0.1 ml / €340.00
  Acris Antibodies GmbH

FER / TYK3 pTyr402 antibody

Immunohistochemical analysis of paraffin-embedded human brain tissue using FER (Phospho-Tyr402) antibody AP55754PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms P, WB
50 µl / €270.00
  Acris Antibodies GmbH

FER / TYK3 pTyr402 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using FER (Phospho-Tyr402) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
50 µg / €230.00
  Assay Biotech

FER / TYK3 pTyr402 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using FER (Phospho-Tyr402) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €330.00
  Assay Biotech

FER / TYK3 antibody

Western blot analysis of extracts from Jurkat/HuvEc cells, using FER Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

FER / TYK3 antibody

Western blot analysis of extracts from Jurkat/HuvEc cells, using FER Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

FER - human gene knockout kit via CRISPR

FER - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

FER - human gene knockout kit via CRISPR

FER - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

FER - human gene knockout kit via CRISPR

FER - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

FER - human gene knockout kit via CRISPR

FER - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Fert2 - mouse gene knockout kit via CRISPR

Fert2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

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