FFR / ANG2 antibody

Principal name

FFR / ANG2 antibody

Alternative names for FFR / ANG2 antibody

C11orf2, PP5382, Protein fat-free homolog, Another new gene 2 protein

SwissProt ID

A6QQ47 (Bovin), Q3UVL4 (Mouse), Q505L3 (Xenla), Q5ZJ25 (Chick), Q9UID3 (Human)

Gene ID

25858 (C11orf20), 738 (C11orf2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of FFR / ANG2 antibody

Fat Free Antibody: Fat Free, also known as ANG2, was identified though a yeast two-hybrid screen using VP53. It is thought to be a structural and functiol homolog of the yeast protein VPS51, a protein that together with VPS52, VPS53, and VPS54 form the Golgi-associated retrograde protein (GARP) complex that mediates the tethering and fusion of endosome-derived transport carriers to the trans-Golgi network (TGN). Similar to depletion of any of the VPS52, VPS53, or VPS54, depletion of Fat Free using Ri impairs protein retrieval to the TGN indicating that Fat Free is missing component of the GARP complex in most eukaryotes.

General readings

Perez-Victoria FJ, Schindler C, Magadan JG, et al. Ang2/Fat Free is a conserved subunit of the Golgi-associated retrograde protein complex. Mol. Biol. Cell 2010; 21:3386-95
Ho SY, Lorent K, Pack M, et al. Zebrafish Fat Free is required for intestinal lipid absorption and Golgi apparatus structure. Cell Metab. 2006; 3:289-300.
Perez-Victoria FJ, Mardones GA, and Bonifacino JS. Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes. Mol. Biol. Cell 2008; 19:2350-62
Stafford RL, Ear J, Knight MJ, et al. The molecular basis of the Caskin1 and Mint1 interaction with CASK. J. Mol. Biol. 2011; 412:3-13.

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FFR / ANG2 antibody

Sample (30 ug of whole cell lysate). A: A431 . B: Hela. 7.5% SDS PAGE. TA308857 diluted at 1:1000. Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FFR / ANG2 (C-term) antibody

Western blot analysis of Fat Free in mouse brain tissue lysate with Fat Free antibody at 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FFR / ANG2 antibody

WB Suggested Anti-C11orf2 Antibody; Titration: 1.0 ug/ml; Positive Control: 293T Whole CellVPS51 is supported by BioGPS gene expression data to be expressed in HEK293T Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

FFR / ANG2 (C-term) Control Peptide

FFR / ANG2
50 µg / €160.00
  Acris Antibodies GmbH

FFR / ANG2 antibody

Immunohistochemistry-Paraffin: C11orf2 Antibody [NBP1-90857] - Immunohistochemical staining of human cerebellum shows strong nuclear and cytoplasmic positivity in Purkinje cells. Rabbit Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

5 Item(s)

per page
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