FGD1 antibody

Principal name

FGD1 antibody

Alternative names for FGD1 antibody

FGDY, ZFYVE3, FYVE, RhoGEF and PH domain-containing protein 1, Faciogenital dysplasia 1 protein, Zinc finger FYVE domain-containing protein 3, Rho/Rac guanine nucleotide exchange factor FGD1

SwissProt ID

P52734 (Mouse), P98174 (Human)

Gene ID

2245 (FGD1)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB)

Background of FGD1 antibody

FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kise cascade leading to c-Jun kise SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kise cascade leading to c-Jun kise SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.

General readings

Lebel,R.R., et al., (2002) Clin. Genet. 61 (2), 139-145

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FGD1 antibody

  Rabbit Polyclonal Anti-FGD1 Antibody  
WB Suggested Anti-FGD1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Transfected 293T Rabbit IgG Purified Bov, Hu, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

FGD1 - human gene knockout kit via CRISPR

FGD1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

FGD1 - human gene knockout kit via CRISPR

FGD1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

FGD1 - human gene knockout kit via CRISPR

FGD1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

FGD1 - human gene knockout kit via CRISPR

FGD1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FGD1

  Recombinant protein of human FYVE, RhoGEF and PH domain containing 1 (FGD1)  
FGD1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, FGD1 (mGFP-tagged) - Human FYVE, RhoGEF and PH domain containing 1 (FGD1), 200 uL, >10^7 TU/mL

Lenti ORF particles, FGD1 (mGFP-tagged) - Human FYVE, RhoGEF and PH domain containing 1 (FGD1), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, FGD1 (Myc-DDK tagged) - Human FYVE, RhoGEF and PH domain containing 1 (FGD1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, FGD1 (Myc-DDK tagged) - Human FYVE, RhoGEF and PH domain containing 1 (FGD1) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

8 Item(s)

per page
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