FGR / SRC2 antibody

Principal name

FGR / SRC2 antibody

Alternative names for FGR / SRC2 antibody

C-FGR, P55-FGR, Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, Proto-oncogene tyrosine-protein kinase FGR

SwissProt ID

P09769 (Human), P14234 (Mouse)

Gene ID

2268 (FGR)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Bov (Bovine), Eq (Equine), Rb (Rabbit)

Available hosts

Goat, Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of FGR / SRC2 antibody

Src is the human homolog of the v-src gene of the Rous sarcoma virus, also called avian sarcoma virus or ASV. Src was the first proto-oncogenic nonreceptor tyrosine kinase characterized in human. By virtue of common structural motifs, the Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Src-family kinases transduce signals that are involved in the control of a variety of cellular processes, including proliferation, differentiation, motility, and adhesion. Src-family kinases contain an amino terminal cell membrane anchor followed by an SH3 domain and an SH2 domain involved in modular association and activation, respectively. Src-family kinases are normally maintained in an inactive state and can be activated transiently during cellular events such as mitosis. Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking. c-Fgr is a human nonreceptor tyrosine kinase family member that was discovered using a probe toward the v-Fgr portion of the cell-derived domain of Gardner-Rasheed feline sarcoma virus. The human c-Fgr gene maps to chromosome 1p36.2-p36.1 and encodes a 529 amino acid protein.

General readings

Katamine S, Notario V, Rao CD, Miki T, Cheah MS, Tronick SR, Robbins KC.
Primary structure of the human fgr proto-oncogene product p55c-fgr.
Mol Cell Biol 1988 Jan;8(1):259-66
PMID: 3275868

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FGR / SRC2 (N-term) antibody

  Rabbit polyclonal FGR Antibody (N-term)  
The anti-FGR Pab (Cat. #TA324973) is used in Western blot to detect FGR in Ramos cell lysate. Rabbit Ig Purified Hu ICC/IF, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

FGR / SRC2 antibody

  Rabbit Polyclonal FGR Antibody  
Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-FGR rabbit polyclonal antibody. (TA590200) Rabbit IgG Purified Hu E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FGR / SRC2 (C-term) antibody

  Goat Polyclonal Antibody against FGR  
TA302485 staining (0.5µg/ml) of Mouse Spleen extracts (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FGR / SRC2 antibody

  Rabbit polyclonal anti-FGR antibody  
Western blot analysis of extracts from HUVEC cells and COLO205 cells, using FGR antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FGR / SRC2 antibody

  Rabbit anti-FGR Polyclonal Antibody  
Western blot analysis of extracts of HL60 cell lines, using FGR antibody. Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FGR / SRC2 antibody

  Rabbit Polyclonal Anti-FGR Antibody  
WB Suggested Anti-FGR Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: U937 cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

FGR / SRC2 antibody

Immunohistochemical analysis of paraffin-embedded human Spleen tissues using FGR antibody Cat.-No AM06312SU-N Mouse IgG1 6G2 Ascites Hu, Ms E, P, WB
0.1 ml / €440.00
  Acris Antibodies GmbH

FGR / SRC2 antibody

Western blot(WB) analysis of c-Fgr antibody (Cat.-No.: AP06661PU-N) in extracts from HUVEC cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

FGR / SRC2 antibody

FGR / SRC2 Goat Purified Hu, Ms WB
0.1 mg / €540.00
  Acris Antibodies GmbH

FGR / SRC2 antibody

Western blot analysis of extracts from RAW264.7 cells, using FGR (Ab-412) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €230.00
  Assay Biotech

FGR / SRC2 antibody

Western blot analysis of extracts from RAW264.7 cells, using FGR (Ab-412) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €330.00
  Assay Biotech

FGR / SRC2 antibody

Western blot analysis of extracts from HuvEc/COLO205 cells, using FGR Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

FGR / SRC2 antibody

Western blot analysis of extracts from HuvEc/COLO205 cells, using FGR Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

FGR - human gene knockout kit via CRISPR

FGR - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

FGR - human gene knockout kit via CRISPR

FGR - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

FGR - human gene knockout kit via CRISPR

FGR - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

FGR - human gene knockout kit via CRISPR

FGR - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FGR / SRC2 (transcript variant 1)

  Recombinant protein of human Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog (FGR), transcript variant 1  
FGR / SRC2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

FGR overexpression lysate

FGR overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

FGR overexpression lysate

FGR overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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