Fibrillin-1 antibody

Principal name

Fibrillin-1 antibody

Alternative names for Fibrillin-1 antibody

FBN1, FBN

SwissProt ID

P35555 (Human), P98133 (Bovin), Q61554 (Mouse), Q9TV36 (Pig)

Gene ID

2200 (FBN1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Por (Porcine), Rt (Rat), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoelectron Microscopy (EM)

Background of Fibrillin-1 antibody

The fibrillin family of proteins, including fibrillin-1 (FBN1) and fibrillin-2 (FBN2), are integral components of a distinct subset of extracellular microfibrils. Microfibrils are found in elastic tissues where they facilitate elastic fiber formation and in nonelastic tissue where they support the association of the epithelial cells with the interstitial matrix. Characteristic of the fibrillin proteins are the epidermal growth factor (EGF)-like motifs, which contain a consensus sequence for calcium binding. This calcium association may be critical for protein-protein interactions and stabilization of the microfibrils. Mutations of the FBN1 gene have been shown to result in Marfan syndrome, a disease characterized by abnormal synthesis, secretion and matrix deposition of fibrillin. FBN2 is also linked to a rare, yet similiar, skeletal disorder, congenital contractural arachnodactyly.

General readings

Uyeda,T., et al., (2004) J. Hum. Genet. 49 (8), 404-407

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Fibrillin-1 antibody

  Rabbit polyclonal Fibrillin-1 antibody  
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using Fibrillin-1 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Fibrillin-1 antibody

  Anti-FBN1 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human thyroid cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using FBN1 antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Fibrillin-1 antibody

  Anti-FBN1 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human thyroid cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using FBN1 antibody at dilution 1/47, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Fibrillin-1 antibody

  Rabbit Polyclonal Anti-FBN1 Antibody  
WB Suggested Anti-FBN1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

Fibrillin-1 antibody

Fibrillin-1 Mouse IgG1 11C1.3 Biotin Bov, Hu C, EM, ICC/IF, WB
0.2 mg / €490.00
  Acris Antibodies GmbH

Fibrillin-1 antibody

Fibrillin-1 Mouse IgG1 11C1.3 FITC Bov, Hu C, ICC/IF
0.2 mg / €480.00
  Acris Antibodies GmbH

Fibrillin-1 antibody

Fibrillin-1 Mouse IgG1 11C1.3 Purified Bov, Hu C, EM, ICC/IF, WB
0.2 mg / €380.00
  Acris Antibodies GmbH

Fibrillin-1 (2772-2872) antibody

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a 3H6 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

Fibrillin-1 antibody

Immunohistochemistry analysis of Fibrillin-1 Antibody (Cat.-No AP06122PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Fibrillin-1 antibody

Fibrillin-1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Fibrillin-1 antibody

Immunoperoxidase of monoclonal antibody to FBN1 on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml] Mouse IgG2a 3H6 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Fibrillin-1 antibody

Fibrillin-1 Mouse IgG1 11C1.3 Bov, Hu C, ICC/IF, WB
0.2 mg / €470.00
  Abnova Taiwan Corp.

Fibrillin-1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Fibrillin-1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
50 µg / €230.00
  Assay Biotech

Fibrillin-1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Fibrillin-1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €330.00
  Assay Biotech

Fibrillin-1 antibody

Human Jurkat; WB Suggested Anti-FBN1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Jurkat cell lysate; FBN1 antibody - N-terminal region (ARP37969_P050) in Human Jurkat cells using Western Blot Rabbit IgG Aff - Purified Bov, Can, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Fibrillin-1 antibody

Western blot analysis of Fibrillin 1 expression in Jurkat (A); NIH3T3 (B) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Ms, Por, Rt ICC/IF, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Fibrillin-1 antibody

Western blot analysis of Fibrillin 1 expression in Jurkat (A); NIH3T3 (B) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Ms, Por, Rt ICC/IF, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Fibrillin-1 antibody

Western blot analysis of Fibrillin 1 expression in Jurkat (A); NIH3T3 (B) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Ms, Por, Rt ICC/IF, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CRISPR

Catalog No. Species Donor Vector  

FBN1 - human gene knockout kit via CRISPR

FBN1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

FBN1 - human gene knockout kit via CRISPR

FBN1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

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