Fibrillin-1 antibody

Principal name

Fibrillin-1 antibody

Alternative names for Fibrillin-1 antibody

FBN1, FBN

SwissProt ID

P35555 (Human), P98133 (Bovin), Q61554 (Mouse), Q9TV36 (Pig)

Gene ID

2200 (FBN1), 281154

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Por (Porcine), Chk (Chicken), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoelectron Microscopy (EM), Paraffin Sections (P), Immunoprecipitation (IP)

Background of Fibrillin-1 antibody

Fibrillin is the major constitutive element of extracellular microfibrils and has widespread distribution in both elastic and nonelastic connective tissue throughout the body. The cDNA was identified in 1991 and was mapped coincident with the locus for Marfan syndrome. Subsequent studies confirmed that mutations in the Fibrillin 1 gene are the major cause of Marfan syndrome. The connective tissue protein has a widespread distribution in the connective tissue matrices of skin, lung, kidney, vasculature, cartilage, tendon, muscle, cornea, and ciliary zonule. Fibrillin 1 is an extracellular acidic protein with a high cysteine content and an extended threadlike shape with mosaic composition of different types of extracellular modules. Most of the fibrillin molecule is contributed by 47 epidermal growth factor like (EGF like) repeats; 43 of them have a consensus sequence for calcium binding (cb). Other modules including 8 cysteine motifs (seven), hybrid motifs (two), and unique domains (three) are interspersed throughout the molecule. Fibrillin 1 contains a proline rich region close to the N terminus that is replaced by a glycine rich region in Fibrillin 2. The fibrillins are found throughout the connective tissue as integral components of extended fibrils.

General readings

General / background references:Maier A et al. Fibrillin and elastin networks in extrafusal tissue and muscle spindles of bovine extraocular muscles. Invest Ophthalmol Vis Sci 35:3103-10 (1994). PubMed PMID: 8206729
Wright DW et al. Immunization with undenatured bovine zonular fibrils results in monoclonal antibodies to fibrillin. Matrix Biol 14:41-9 (1994). PubMed PMID: 8061919

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Fibrillin-1 antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using Fibrillin-1 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Fibrillin-1 antibody

Predicted cell location: Cytoplasm. Positive control: Human thyroid cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using FBN1 antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Fibrillin-1 antibody

Predicted cell location: Cytoplasm. Positive control: Human thyroid cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using FBN1 antibody at dilution 1/47, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Fibrillin-1 antibody

WB Suggested Anti-FBN1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

Fibrillin-1 antibody

Fibrillin-1 Mouse IgG1 11C1.3 Biotin Bov, Hu C, EM, ICC/IF, WB
0.2 mg / €490.00
  Acris Antibodies GmbH

Fibrillin-1 antibody

Fibrillin-1 Mouse IgG1 11C1.3 FITC Bov, Hu C, ICC/IF
0.2 mg / €480.00
  Acris Antibodies GmbH

Fibrillin-1 antibody

Fibrillin-1 Mouse IgG1 11C1.3 Purified Bov, Hu C, EM, ICC/IF, WB
0.2 mg / €380.00
  Acris Antibodies GmbH

Fibrillin-1 (2772-2872) antibody

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a 3H6 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

Fibrillin-1 antibody

Immunohistochemistry analysis of Fibrillin-1 Antibody (Cat.-No AP06122PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Fibrillin-1 antibody

Fibrillin-1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Fibrillin-1 antibody

Immunoperoxidase of monoclonal antibody to FBN1 on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml] Mouse IgG2a 3H6 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Fibrillin-1 antibody

Fibrillin-1 Mouse IgG1 11C1.3 Bov, Hu C, ICC/IF, WB
0.2 mg / €470.00
  Abnova Taiwan Corp.

Fibrillin-1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Fibrillin-1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
50 µg / €205.00
  Assay Biotech

Fibrillin-1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Fibrillin-1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €310.00
  Assay Biotech

Fibrillin-1 antibody

Human Jurkat; WB Suggested Anti-FBN1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Jurkat cell lysate; FBN1 antibody - N-terminal region (ARP37969_P050) in Human Jurkat cells using Western Blot Rabbit IgG Aff - Purified Bov, Can, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Fibrillin-1 antibody

Western blot analysis of Fibrillin 1 expression in Jurkat (A); NIH3T3 (B) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Ms, Por, Rt ICC/IF, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Fibrillin-1 antibody

Western blot analysis of Fibrillin 1 expression in Jurkat (A); NIH3T3 (B) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Ms, Por, Rt ICC/IF, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Fibrillin-1 antibody

Western blot analysis of Fibrillin 1 expression in Jurkat (A); NIH3T3 (B) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Ms, Por, Rt ICC/IF, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Fibrillin-1 antibody

Fibrillin-1 Rabbit Hu E, WB
50 µg / €400.00
  Novus Biologicals Inc.

Fibrillin-1 antibody

Fibrillin-1 Rabbit IgG Aff - Purified Hu, Ms, Rt P
0.1 mg / €420.00
  Novus Biologicals Inc.

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