Fibrinogen alpha chain antibody

Principal name

Fibrinogen alpha chain antibody

Alternative names for Fibrinogen alpha chain antibody

FGA

SwissProt ID

P02671 (Human), P02672 (Bovin), P06399 (Rat), P14448 (Chick), P14452 (Horse), P14460 (Pig), P68213 (Canfa)

Gene ID

2243 (FGA), 522039

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Rt (Rat), Can (Canine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), ELISA (capture) (E(capture)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunoprecipitation (IP), Radioimmunoassay (R), EPair for Elisa (EPair), Frozen Sections (C), Immunodiffusion (ID)

Background of Fibrinogen alpha chain antibody

Fibrinogen (clotting factor I) is a heat labile beta glycoprotein (molecular weight 340,000) and consists of three pairs of chains bound by disulphide bonds. It is synthesized in hepatocytes under genetic control. It is the precursor of fibrin, which is the key protein constituting the network of the blood clot. Thrombin converts fibrinogen to fibrin by limited proteolysis, releasing the fibrinopeptides A and B (molecular weight 50,000-65,000) and forming fibrin monomers. Fibrin monomers polymerize to fibrin which is stabilized by cross-linking under the influence of factor XIII. The predominant gamma chain of normal fibrinogen (MW 50,000, with higher variants) has a low affinity for platelet binding. 
The normal concentration of fibrinogen in the blood is 2.5 to 3.5 ml /ml, but lower levels are usually adequate for haemostasis. In newborn infants the value is 1.2 to 2.4 mg/ml. Synthesis of foetal fibrinogen may persists for up to 8 weeks, when adult levels are reached. Adult level increase with age and are a risk for heart disease, myocardial infarction and stroke. Fibrinogen is an acute Phase protein and increased levels are found in loosing enteropathies, in severe malnutrition, in tissue necrosis and in malignancy. Extremely high levels are seen in acute pancreatitis and, to a lower extent, in nephritic syndrome. A moderate raise may also been seen during pregnancy and the use of oral contraceptives. Fibrinogen deficiency may be congenital or acquired. If sufficiently severe, it may result in a bleeding disorder. The congenital form is very rare. Acquired hypofibrinogaemia is relatively common, probably indicating increased consumption during intravascular clotting.

General readings

Smolarczyk,K., (2005) Arterioscler. Thromb. Vasc. Biol. 25 (12), 2679-2684

  1. Quick-Filters:
  2. Highly Validated (1)

Items 1 to 20 of 33 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Fibrinogen antibody

Fibrinogen Rabbit Serum Hu ID, IP, P
1 ml / €190.00
  Acris Antibodies GmbH

Fibrinogen alpha chain antibody

Immunoperoxidase of purified MaxPab rabbit antibody to FGA on formalin-fixed paraffin-embedded human ovary. [antibody concentration 1.5 ug/ml] Rabbit Purified Hu, Ms E(detection), P, WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Fibrinogen alpha chain antibody

Western Blot of Goat anti-Fibrinogen antibody. Lane 1: Fibrinogen under reducing conditions. Lane 2: none. Load: 1 µg per lane. Primary antibody: Fibrinogen antibody at 1:3000 for overnight at 4°C. Secondary antibody: Dylight 488 conjugated Donkey anti goat secondary antibody at 1:10,000 for 45 min at RT. Block: TBS/MB-070 1 hr RT. Goat Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Fibrinogen alpha chain (N-term) antibody

FGA Antibody (N-term) (Cat. #TA324872) western blot analysis in human blood plasma tissue lysates (35ug/lane).This demonstrates the FGA antibody detected the FGA protein (arrow). Rabbit Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Fibrinogen alpha chain (123-135) antibody

TA348926 (0.01 ug/ml) staining of Human Platelets lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Fibrinogen alpha chain antibody

TA348964 (0.01 ug/ml) staining of Platelets lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Fibrinogen alpha chain antibody

Fibrinogen alpha chain Mouse IgM MFB-HB Purified Can, Hu C, E, ICC/IF
1 ml / €310.00
  Acris Antibodies GmbH

Fibrinogen alpha chain (beta, gamma) antibody

Fibrinogen alpha chain Goat Serum Hu E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

Fibrinogen alpha chain antibody

Fibrinogen alpha chain Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Fibrinogen alpha chain antibody

Western Blot analysis of FGA expression in transfected 293T cell line (H00002243-T03) by FGA MaxPab polyclonal antibody.

Lane 1: FGA transfected lysate(24.70 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Fibrinogen alpha chain antibody

Fibrinogen alpha chain Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Fibrinogen alpha chain antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between APOA1 and FGA. HeLa cells were stained with anti-APOA1 rabbit purified polyclonal 1:1200 and anti-FGA mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Mouse IgG2a 1D12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Fibrinogen alpha chain antibody

Fibrinogen alpha chain Rabbit Hu E, IP, R
0.4 mg / €390.00
  Abnova Taiwan Corp.

Fibrinogen alpha chain antibody

Human Skin; Rabbit Anti-FGA Antibody. Catalog Number: ARP41758. Paraffin Embedded Tissue: Human Skin. Cellular Data: Squamous epithelial cells. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; FGA antibody - N-terminal region (ARP41758_T100) in Human Skin cells using Immunohistochemistry Rabbit Aff - Purified Bov, Hu, Ms P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

Fibrinogen alpha chain antibody

Human HeLa; WB Suggested Anti-FGA Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:12500. Positive Control: Hela cell lysate; FGA antibody - middle region (ARP41759_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Fibrinogen alpha chain (Prolyl 4-Hydroxylated) antibody

Fibrinogen alpha chain Mouse IgG1 11A5 Purified Hu ELISA, WB
50 µg / €700.00
  Funakoshi Co., Ltd.

Fibrinogen alpha chain antibody

Western Blot: Fibrinogen Antibody (1F9) [NBP1-47442] - Western blot analysis using anti-FGB mAb against human plasma (1). Mouse IgG1 1F9 Purified Hu E, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Fibrinopeptide A antibody

Fibrinopeptide A Rabbit Serum Hu ID, IP
1 ml / €360.00
  Acris Antibodies GmbH

Fibrinopeptide A antibody

Fibrinopeptide A Mouse IgG2a 1F7 Hu E
0.2 mg / €470.00
  Abnova Taiwan Corp.

Fibrinopeptide A antibody

Fibrinopeptide A Mouse IgG2a 49D2 Hu E
0.2 mg / €470.00
  Abnova Taiwan Corp.

Items 1 to 20 of 33 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn