Fibrinogen antibody

Principal name

Fibrinogen antibody

Alternative names for Fibrinogen antibody

FGA, FGB, FGG

Available reactivities

Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Can (Canine)

Available hosts

Mouse, Goat, Sheep, Rabbit, Chicken

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (capture) (E(capture)), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Radioimmunoassay (R), Immunodiffusion (ID), Dot blot (Dot)

Background of Fibrinogen antibody

Fibrinogen is a protein produced by the liver which helps stop bleeding by helping blood clots to form. Fibrinogen gets deiminated (conversion from arginin to citrullin) by Peptidyl Arginine Deïminase (PAD) in inflamed joints in patients that develop rheumatoid arthritis.Citrulline, while being an amino acid, is not built into proteins during protein synthesis, as it is not coded for by DNA, yet several proteins are known to contain citrulline. These citrulline residues are generated by a family of enzymes called peptidylarginine deiminases (PADs), which convert arginine into citrulline in a process called citrullination or deimination. Proteins that normally contain citrulline residues include myelin basic protein (MBP), filaggrin, and several histone proteins, while other proteins, like fibrin and vimentin can get citrullinated during cell death and tissue inflammation. Patients with rheumatoid arthritis often (at least 80% of them) develop an immune response against proteins containing citrulline. Although the origin of this immune response is not known, detection of antibodies reactive with citrulline containing proteins or peptides is now becoming an important help in the diagnosis of rheumatoid arthritis.

General readings

Lowe G et al. Blood rheology, cardiovascular risk factors, and cardiovascular disease: the West of Scotland Coronary Prevention Study. Thromb Haemost 84:553-8 (2000). PubMed PMID: 11057849
Danesh J et al. Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of prospective studies. JAMA 279:1477-82 (1998). PubMed PMID: 9600484

  1. Quick-Filters:
  2. Cited (4)

Items 1 to 20 of 61 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Fibrinogen antibody

Fibrinogen Rabbit Purified Ms E, WB
1 mg / €620.00
  Acris Antibodies GmbH

Fibrinogen antibody

Liver: Formalin-Fixed Paraffin-Embedded (FFPE) Goat IgG Purified Hu E, ICC/IF, IP, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

Fibrinogen (citrullinated) antibody

Figure.1: Specificity of Anti-Citrullinated Fibrinogen Immunoglobulin, clone 3F2, determined by Immunoblot analysis. Blot contains Human Fibrinogen  in the left lane and Rabbit PAD2 deiminated Human Fibrinogen in the right lane. 
Incubated with antibody fraction (0.5 mg/ml) 1000X diluted in PBS containing 0,05% tween-20 and 5% non fat dry milk. Mouse IgG2a 3F2 Purified Hu E, WB
0.1 mg / €800.00
  Acris Antibodies GmbH

Fibrinogen (citrullinated) antibody

Figure 1: Specificity of Anti-Deiminated Murine Fibrinogen Immunoglobulin, clone 23H2, determined by ELISA. Antibody fraction (0.5 mg/ml) 1000X diluted in PBS containing 0.05% tween-20 and 5% non fat dry milk. Antibody was tested on both Rabbit PAD2 deiminated as non deiminated Murine Fibrinogen. Mouse IgG1 23H2 Purified Hu, Ms C, E, F
0.1 mg / €600.00
  Acris Antibodies GmbH

Fibrinogen (citrullinated) antibody

Fibrinogen Mouse IgG1 4.19D5 Purified Hu E
0.1 mg / €600.00
  Acris Antibodies GmbH

Fibrinogen (citrullinated) antibody

Figure 1: Specificity of Anti- Deiminated Murine Fibrinogen Immunoglobulin, clone 20B2, determined by ELISA. Antibody fraction (0.5 mg/ml) 2000X diluted in PBS containing 0.05% tween-20 and 5% non fat dry milk. Antibody was tested on both rabbit PAD2 deiminated as non deiminated Murine Fibrinogen. Mouse IgG1 20B2 Purified Hu, Ms E
0.1 mg / €600.00
  Acris Antibodies GmbH

Fibrinogen (citrullinated) antibody

Figure 1: Specificity of Anti- Deiminated Murine Fibrinogen Immunoglobulin, clone 3D1, determined by ELISA. Antibody fraction (0.5 mg/ml) 2000X diluted in PBS containing 0,05% tween-20 and 5% non fat dry milk. Antibody was tested on both rabbit PAD2 deiminated as non deiminated Murine Fibrinogen. Mouse IgG1 3D1 Purified Hu, Ms E
0.1 mg / €600.00
  Acris Antibodies GmbH

Fibrinogen (Oxidized), (Insoluble Fraction) antibody

Fibrinogen Rabbit Serum Hu E
0.1 ml / €330.00
  Acris Antibodies GmbH

Fibrinogen (Oxidized), (Insoluble Fraction) antibody

Fibrinogen Rabbit Serum Hu E
20 µl / €140.00
  Acris Antibodies GmbH

Fibrinogen (Oxidized), (Soluble Fraction) antibody

Fibrinogen Rabbit Serum Hu E
0.1 ml / €330.00
  Acris Antibodies GmbH

Fibrinogen (Oxidized), (Soluble Fraction) antibody

Fibrinogen Rabbit Serum Hu E
20 µl / €140.00
  Acris Antibodies GmbH

Fibrinogen (Oxidized), (Total Fraction) antibody

Fibrinogen Rabbit Serum Hu E
0.1 ml / €330.00
  Acris Antibodies GmbH

Fibrinogen (Oxidized), (Total Fraction) antibody

Fibrinogen Rabbit Serum Hu E
20 µl / €140.00
  Acris Antibodies GmbH

Fibrinogen antibody

Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) using anti-Fibrinogen antibody (Cat#AP08879PU-N) Sheep IgG Purified Hu, Ms, Rt C, E, ICC/IF, P
0.25 mg / €470.00
  Acris Antibodies GmbH

Fibrinogen antibody

Formalin-Fixed Paraffin Embedded Human Kidney stained with Fibrinogen antibody Cat.-No AP09026PU-N at 5 µg/ml after heat-induced antigen retrieval. Goat IgG Ig Fraction Hu E, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

Fibrinogen antibody

Fibrinogen Goat IgG Azide Free Can ID, IP
10 mg / €380.00
  Acris Antibodies GmbH

Fibrinogen antibody

Fibrinogen Goat IgG FITC Can E, ICC/IF, ID, IP
1 ml / €340.00
  Acris Antibodies GmbH

Fibrinogen antibody

Fibrinogen Goat IgG HRP Can C, E, ICC/IF, ID, IP, WB
1 ml / €340.00
  Acris Antibodies GmbH

Fibrinogen antibody

Fibrinogen Goat Serum Can ID, IP
1 ml / €250.00
  Acris Antibodies GmbH

Fibrinogen antibody

Fibrinogen Goat IgG Azide Free Ms Dot, E, ICC/IF, ID, IP, WB
10 mg / €380.00
  Acris Antibodies GmbH

Items 1 to 20 of 61 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4
  • LinkedIn