Ficolin-2 antibody

Principal name

Ficolin-2 antibody

Alternative names for Ficolin-2 antibody

FCN2, FCNL, Ficolin2, Ficolin-B, Ficolin-beta, L-ficolin, Serum lectin p35, 37 kDa elastin-binding protein, EBP-37, Hucolin, Collagen/fibrinogen domain-containing protein 2

SwissProt ID

O70497 (Mouse), P57756 (Rat), Q15485 (Human), Q29041 (Pig), Q5I2E5 (Bovin)

Gene ID

2220 (FCN2), 14134 (Fcnb), 114091

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit, Rat

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Enzyme Immunoassay (E)

Background of Ficolin-2 antibody

Ficolins are members of the collectin family of proteins which recognize PAMP on microbial surfaces. Human and murine ficolins differ in many aspects. Mouse has two ficolin forms, termed ficolin-A and -B. Mouse ficolin-A is the plasma protein, highly expressed in liver and spleen. Mouse ficolin-B is expressed in spleen, bone marrow, and peritoneal macrophages. It is thought to facilitate phagocytosis and is involved in the activation of complement pathways. 
Structure: Ficolin consists of a short N-terminal, the middle collagen-like domain and C-terminal fibrionogen domain. The collagen-like domain assemble the subunits into trimers and the N-terminal domain further assembles four trimers into 12-mers.
Distribution: In contrast to human ficolin B, mouse ficolin B is mainly produced by macrophages.
Function: Recognize pathogen-associated molecular pattern ( PAMP) on microbial surface to facilitate phagocytosis. In addition, it can activate complement through a calcium-dependent association with MASPs.

20 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Ficolin-2 antibody

  Rat Monoclonal anti-Ficolin B Antibody  
Mouse macrophage (lane 1), liver (lane 2) and spleen (lane 3) cell extracts were resolved by electrophoresis, transferred to nitrocellulose and probed with monoclonal anti-Ficolin B antibody. Proteins were visualized using a goat anti-rat secondary conjugated to HRP and a chemiluminescence detection system. Rat IgG2b IA4 Purified Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Ficolin-2 antibody

  Rat Monoclonal anti-Ficolin B Antibody  
Mouse macrophage (lane 1), liver (lane 2) and spleen (lane 3) cell extracts were resolved by electrophoresis, transferred to nitrocellulose and probed with monoclonal anti-Ficolin B antibody. Proteins were visualized using a goat anti-rat secondary conjugated to HRP and a chemiluminescence detection system. Rat IgG2b IA4 Purified Ms WB
25 µg / €248.00
  OriGene Technologies, Inc.

Ficolin-2 antibody

Ficolin-2 Mouse IgG1 GN4 Biotin Hu E, IP
50 µg / €350.00
  Acris Antibodies GmbH

Ficolin-2 antibody

Ficolin-2 Mouse IgG1 GN4 Purified Hu E, IP
0.1 mg / €500.00
  Acris Antibodies GmbH

Ficolin-2 antibody

Ficolin-2 Mouse IgG1 GN5 Purified Hu E, IP, WB
0.1 mg / €500.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Fcnb - mouse gene knockout kit via CRISPR

Fcnb - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Fcnb - mouse gene knockout kit via CRISPR

Fcnb - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Fcnb - mouse gene knockout kit via CRISPR

Fcnb - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Fcnb - mouse gene knockout kit via CRISPR

Fcnb - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Ficolin-2 (transcript variant SV1)

  Recombinant protein of human ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) (FCN2), transcript variant SV1  
Ficolin-2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

ELISA Kits

Catalog No.    

Human Ficolin-2 ELISA Kit

Human Ficolin-2 ELISA Kit  
1 kit / €389.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

FCN2 overexpression lysate

FCN2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, FCN2 (mGFP-tagged)-Human ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) (FCN2), transcript variant SV0, 200 uL, >10^7 TU/mL

Lenti ORF particles, FCN2 (mGFP-tagged)-Human ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) (FCN2), transcript variant SV0, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, FCN2 (mGFP-tagged) - Human ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) (FCN2), transcript variant SV1, 200 uL, >10^7 TU/mL

Lenti ORF particles, FCN2 (mGFP-tagged) - Human ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) (FCN2), transcript variant SV1, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, FCN2 (Myc-DDK-tagged)-Human ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) (FCN2), transcript variant SV0, 200 uL, >10^7 TU/mL

Lenti ORF particles, FCN2 (Myc-DDK-tagged)-Human ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) (FCN2), transcript variant SV0, 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Lenti ORF particles, FCN2 (Myc-DDK tagged) - Human ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) (FCN2), transcript variant SV1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, FCN2 (Myc-DDK tagged) - Human ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) (FCN2), transcript variant SV1 , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Fcnb (GFP-tagged) - Mouse ficolin B (Fcnb), 200 uL, >10^7 TU/mL

Lenti ORF particles, Fcnb (GFP-tagged) - Mouse ficolin B (Fcnb), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Fcnb (Myc-DDK-tagged) - Mouse ficolin B (Fcnb), 200 uL, >10^7 TU/mL

Lenti ORF particles, Fcnb (Myc-DDK-tagged) - Mouse ficolin B (Fcnb), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Fcnb (GFP-tagged ORF) - Rat ficolin B (Fcnb), 200 uL, >10^7 TU/mL

Lenti ORF particles, Fcnb (GFP-tagged ORF) - Rat ficolin B (Fcnb), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Fcnb (Myc-DDK-tagged ORF) - Rat ficolin B (Fcnb), 200 uL, >10^7 TU/mL

Lenti ORF particles, Fcnb (Myc-DDK-tagged ORF) - Rat ficolin B (Fcnb), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

20 Item(s)

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