Ficolin-2 antibody

Principal name

Ficolin-2 antibody

Alternative names for Ficolin-2 antibody

FCN2, FCNL, Ficolin2, Ficolin-B, Ficolin-beta, L-ficolin, Serum lectin p35, 37 kDa elastin-binding protein, EBP-37, Hucolin, Collagen/fibrinogen domain-containing protein 2

SwissProt ID

O70497 (Mouse), P57756 (Rat), Q15485 (Human), Q29041 (Pig), Q5I2E5 (Bovin)

Gene ID

2220 (FCN2), 14134 (Fcnb), 114091

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit, Rat

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Enzyme Immunoassay (E)

Background of Ficolin-2 antibody

Ficolins are members of the collectin family of proteins which recognize PAMP on microbial surfaces. Human and murine ficolins differ in many aspects. Mouse has two ficolin forms, termed ficolin-A and -B. Mouse ficolin-A is the plasma protein, highly expressed in liver and spleen. Mouse ficolin-B is expressed in spleen, bone marrow, and peritoneal macrophages. It is thought to facilitate phagocytosis and is involved in the activation of complement pathways. 
Structure: Ficolin consists of a short N-terminal, the middle collagen-like domain and C-terminal fibrionogen domain. The collagen-like domain assemble the subunits into trimers and the N-terminal domain further assembles four trimers into 12-mers.
Distribution: In contrast to human ficolin B, mouse ficolin B is mainly produced by macrophages.
Function: Recognize pathogen-associated molecular pattern ( PAMP) on microbial surface to facilitate phagocytosis. In addition, it can activate complement through a calcium-dependent association with MASPs.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Ficolin-2 antibody

  Rat Monoclonal anti-Ficolin B Antibody  
Mouse macrophage (lane 1), liver (lane 2) and spleen (lane 3) cell extracts were resolved by electrophoresis, transferred to nitrocellulose and probed with monoclonal anti-Ficolin B antibody. Proteins were visualized using a goat anti-rat secondary conjugated to HRP and a chemiluminescence detection system. Rat IgG2b IA4 Purified Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Ficolin-2 antibody

  Rat Monoclonal anti-Ficolin B Antibody  
Mouse macrophage (lane 1), liver (lane 2) and spleen (lane 3) cell extracts were resolved by electrophoresis, transferred to nitrocellulose and probed with monoclonal anti-Ficolin B antibody. Proteins were visualized using a goat anti-rat secondary conjugated to HRP and a chemiluminescence detection system. Rat IgG2b IA4 Purified Ms WB
25 µg / €248.00
  OriGene Technologies, Inc.

Ficolin-2 antibody

Ficolin-2 Mouse IgG1 GN4 Biotin Hu E, IP
50 µg / €350.00
  Acris Antibodies GmbH

Ficolin-2 antibody

Ficolin-2 Mouse IgG1 GN4 Purified Hu E, IP
0.1 mg / €500.00
  Acris Antibodies GmbH

Ficolin-2 antibody

Ficolin-2 Mouse IgG1 GN5 Purified Hu E, IP, WB
0.1 mg / €500.00
  Acris Antibodies GmbH

Ficolin-2 antibody

Western Blot analysis of FCN2 expression in transfected 293T cell line (H00002220-T01) by FCN2 MaxPab polyclonal antibody.

Lane 1: FCN2 transfected lysate(34.43 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Ficolin-2 antibody

Ficolin-2 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Ficolin-2 antibody

Western Blot analysis of FCN2 expression in transfected 293T cell line (H00002220-T02) by FCN2 MaxPab polyclonal antibody.

Lane 1: FCN2 transfected lysate(34.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

Ficolin-2 antibody

FCN2 MaxPab rabbit polyclonal antibody. Western Blot analysis of FCN2 expression in human colon. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Ficolin-2 antibody

Human NCI-H226; WB Suggested Anti-FCN2 Antibody Titration: 0.2-1 ug/ml. Positive Control: NCI-H226 cell lysate. FCN2 is strongly supported by BioGPS gene expression data to be expressed in Human NCI-H226 cells.; FCN2 antibody - N-terminal region (ARP42172_P050) in Human NCI-H226 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CRISPR

Catalog No. Species Donor Vector  

Fcnb - mouse gene knockout kit via CRISPR

Fcnb - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Fcnb - mouse gene knockout kit via CRISPR

Fcnb - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Fcnb - mouse gene knockout kit via CRISPR

Fcnb - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Fcnb - mouse gene knockout kit via CRISPR

Fcnb - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Ficolin-2 (transcript variant SV1)

  Recombinant protein of human ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) (FCN2), transcript variant SV1  
Ficolin-2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Ficolin-2

Ficolin-2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Ficolin-2

Ficolin-2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

FCN2 (Human) IP-WB Antibody Pair

FCN2 (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

ELISA Kits

Catalog No.    

Human Ficolin-2 ELISA Kit

Human Ficolin-2 ELISA Kit  
1 kit / €389.00
  OriGene Technologies, Inc.

Human Ficolin 2 ELISA Kit

Representative Standard Curve  
96 Tests / €450.00
  Cohesion Biosciences Ltd.

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