Fidgetin-like protein 1 antibody

Principal name

Fidgetin-like protein 1 antibody

Alternative names for Fidgetin-like protein 1 antibody

FIGNL1

SwissProt ID

Q6DDU8 (Xenla), Q6GX84 (Rat), Q6PIW4 (Human), Q8BPY9 (Mouse)

Gene ID

63979 (FIGNL1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of Fidgetin-like protein 1 antibody

FIGNL1 is a 674 amino acid protein belonging to the AAA ATPase family. FIGNL1 exists as a hexamer that undergoes alternative splicing to produce two isoforms. FIGNL1 utilizes magnesium as a cofactor and is phosphorylated upon DNA damage, probably by ATM or ATR. FIGNL1 is suggested to regulate osteoblast proliferation and differentiation. FIGNL1 is encoded by a gene located on human chromosome 7, which consists about 158 milllion bases, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Fidgetin-like protein 1 antibody

Western Blot and Immunoprecipitation: FIGNL1 Antibody [NB100-2355] - Detection of Human and Mouse FIGNL1 on HeLa whole cell lysate using NB100-2355. FIGNL1 was also immunoprecipitated by other rabbit anti-FIGNL1 antibodies and NB100-2356. Rabbit Aff - Purified Hu, Ms IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Fidgetin-like protein 1 antibody

Western Blot: FIGNL1 Antibody [NB100-2356] - Detection of Human FIGNL1 by Western Blot of  Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP,  20% of IP loaded) from HeLa cells.  Antibodies:  Affinity purified  rabbit anti-FIGNL1 antibody NB100-2356  used for IP at 3 mcg/mg lysate. FIGNL1 was also  immunoprecipitated by other rabbit anti-FIGNL1 antibodies and NB100-2355.  Detection:  Chemiluminescence with an  exposure time of 30 seconds. Rabbit Aff - Purified Hu IP
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Fidgetin-like protein 1

Fidgetin-like protein 1 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

FIGNL1 overexpression lysate

FIGNL1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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