Filaggrin antibody

Principal name

Filaggrin antibody

Alternative names for Filaggrin antibody

FLG

SwissProt ID

P11088 (Mouse), P20930 (Human)

Gene ID

2312 (FLG)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Paraffin Sections (P), Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of Filaggrin antibody

Filaggrins are an important class of the intermediate filament-associated proteins which interect with keratin intermediate filaments (Ifs) of terminally differentiating mammalian epidermis. Filaggrins exhibit wide species variations.
Filaggrin is expressed only in well-differentiated keratinized epithelial cells. The synthesis of filaggrin varies in types of ichthyosis, and with viral, premalignant and malignant conditions. Filaggrin also appears to be a target molecule for rheumatoid arthritis-specific auto-antibodies in humans. Keratohyalin granules in the granular layer of interfollicular epidermis are predominantly composed of the 400-kD protein profilaggrin. Following a short, unique N-terminal domain, most of the profilaggrin molecule consists of 10 to 12 repeats of the 324-residue filaggrin sequence. Upon terminal differentiation of granular cells, profilaggrin is proteolytically cleaved into filaggrin peptides of approximately 37 kD and the N-terminal domain containing an S100-like calcium-binding domain.

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Filaggrin antibody

Predicted cell location: Cytoplasm. Positive control: Human cervical and esophagus cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using FLG antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Filaggrin antibody

Filaggrin Rabbit Purified Hu C, E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Filaggrin antibody

Filaggrin Mouse IgG1 FLG01 Hu P
1 ml / €560.00
  Abnova Taiwan Corp.

Filaggrin antibody

Western blot analysis of Filaggrin expression in HeLa (A); NS-1 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Filaggrin antibody

Western blot analysis of Filaggrin expression in HeLa (A); NS-1 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Filaggrin antibody

Western blot analysis of Filaggrin expression in HeLa (A); NS-1 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Filaggrin antibody

Immunohistochemistry-Paraffin: Filaggrin Antibody [NBP1-87527] Immunohistochemical staining of human vulva/anal skin shows strong cytoplasmic positivity in superficial layer of squamous epithelium. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Filaggrin antibody

Immunohistochemistry-Paraffin: Filaggrin Antibody [NBP1-87528] Immunohistochemical staining of human vulva/anal skin shows strong cytoplasmic positivity in superficial layers of squamous epithelium. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

8 Item(s)

per page
  • LinkedIn