Filensin antibody

Principal name

Filensin antibody

Alternative names for Filensin antibody

BFSP1, CP115, Beaded filament structural protein 1, Lens fiber cell beaded-filament structural protein CP 115, Lens intermediate filament-like heavy

SwissProt ID

A2AMT1 (Mouse), Q02435 (Rat), Q06002 (Bovin), Q06637 (Chick), Q12934 (Human)

Gene ID

631 (BFSP1), 22631 (Ywhaz)

Available reactivities

Hu (Human), Bov (Bovine), Sh (Sheep), Can (Canine), Ms (Mouse), Rt (Rat), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ye (Yeast)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Paraffin Sections (P)

Background of Filensin antibody

More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and BFSP1 (or CP115), are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament.More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin (or CP115), are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

General / background references:Sandilands A et al. Filensin is proteolytically processed during lens fiber cell differentiation by multiple independent pathways. Eur J Cell Biol 67:238-53 (1995). PubMed PMID: 7588880
Sandilands A et al. Vimentin and CP49/filensin form distinct networks in the lens which are independently modulated during lens fibre cell differentiation. J Cell Sci 108 ( Pt 4):1397-406 (1995). PubMed PMID: 7615661
Georgatos SD et al. The beaded intermediate filaments and their potential functions in eye lens. Bioessays 16:413-8 (1994). PubMed PMID: 8080431
Merdes A et al. Filensin: a new vimentin-binding, polymerization-competent, and membrane-associated protein of the lens fiber cell. J Cell Biol 115:397-410 (1991). PubMed PMID: 1918147

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Filensin antibody

Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-BFSP1 mouse monoclonal antibody. (TA804044) Dilution: 1:150 Mouse IgG1 OTI1F4 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Filensin antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-BFSP1 mouse monoclonal antibody. (TA804071) Dilution: 1:150 Mouse IgG1 OTI2B2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Filensin antibody

Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-BFSP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804079) Mouse IgG2a OTI3H6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Filensin antibody

Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-BFSP1 mouse monoclonal antibody. (TA804135) Dilution: 1:150 Mouse IgG2b OTI3H1 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Filensin antibody

WB Suggested Anti-BFSP1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Por, Rb, Rt, Sh, Ye WB
50 µg / €325.00
  OriGene Technologies, Inc.

Filensin antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BFSP1 (RC213412, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BFSP1. Mouse IgG2a OTI1F1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Filensin antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-BFSP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804041) Mouse IgG2b OTI2D2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Filensin antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-BFSP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804042) Mouse IgG1 OTI1B9 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Filensin antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-BFSP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804043) Mouse IgG1 OTI3C11 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Filensin antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BFSP1 (RC213412, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BFSP1. Mouse IgG1 OTI2C3 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Filensin antibody

Filensin Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Filensin antibody

Filensin Mouse IgG 1B11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Filensin antibody

BFSP1 monoclonal antibody (M02), clone 6B4 Western Blot analysis of BFSP1 expression in HL-60 ( Cat # L014V1 ). Mouse IgG2a 6B4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Filensin antibody

Filensin Mouse IgG2a 1B23 Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Filensin antibody

Filensin Mouse IgG1 FIL-27 Bov, Hu C, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Filensin antibody

Human HeLa; WB Suggested Anti-BFSP1 Antibody Titration: 0.2-1 ug/ml. Positive Control: Hela cell lysate; BFSP1 antibody - N-terminal region (ARP40344_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Filensin antibody

Filensin Mouse IgG1 FIL-27 Ascites Hu C, WB
0.1 mg / €290.00
  Boster Immunoleader

Filensin antibody

Filensin Mouse IgG1 FIL-7B10 Ascites Bov, Hu, Sh ICC/IF, WB
0.1 ml / €340.00
  Novus Biologicals Inc.

Filensin antibody

Immunohistochemistry-Paraffin: Filensin Antibody [NBP1-91902] - Immunohistochemical staining of human kidney shows distinct membranous positivity in renal tubules. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Filensin antibody

Immunohistochemistry-Paraffin: Filensin Antibody [NBP1-91903] - Immunohistochemical staining of human stomach, lower shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

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