FIP1L1 antibody

Principal name

FIP1L1 antibody

Alternative names for FIP1L1 antibody

FIP1-like 1, FIP1, RHE, Pre-mRNA 3'-end-processing factor FIP1, Factor interacting with PAP, Rearranged in hypereosinophilia

SwissProt ID

Q5U317 (Rat), Q6UN15 (Human), Q9D824 (Mouse)

Gene ID

81608 (FIP1L1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of FIP1L1 antibody

The Component of the Cleavage and Polyadenylation Specificity Factor (CPSF) complex plays an important role in the 3'-end formation of pre-mRNA. This complex recognizes the AAUAAA signal sequence and interacts with poly(A) polymerase to process and add to the poly(A) tail. FIP1L1 (FIP1-like 1), also known as Pre-mRNA 3'-end-processing factor FIP1, FIP1 (Factor interacting with PAP) and RHE (Rearranged in hypereosinophilia), is a 594 amino acid nuclear protein that is a component of the CPSF complex. Within the complex, FIP1L1 contributes to the poly(A) recognition and stimulates poly(A) addition. Fusion of the genes encoding FIP1L1 and PDGFRA due to an interstitial deletion on chromosome 4q12 is the cause of hypereosinophilia syndrome, a rare blood disorder characterized by continuous overproduction of eosinophils in the bone marrow that leads to tissue infiltration and organ damage. There are three isoforms of FIP1L1 that are produced as a result of alternative splicing events.

General readings

Zhao,X., (2005) J. Virol. 79 (7), 4270-4288

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FIP1L1 antibody

WB Suggested Anti-FIP1L1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate; FIP1L1 is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

FIP1L1 antibody

FIP1L1 Mouse IgG1 2H4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

FIP1L1 antibody

Human Brain; . Rabbit Anti-FIP1L1 antibody. . Catalog Number:. ARP41031_P050 . Paraffin Embedded Tissue: Human Brain cell . Cellular Data: Epithelial cells of renal tubule. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; FIP1L1 antibody (ARP41031_P050) in Human Brain cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

FIP1L1 antibody

Western Blot and Immunoprecipitation: FIP1 Antibody [NB100-74588] - Detection of Human FIP1 on HeLa whole cell lysate using NB100-74588. FIP1 was also  immunoprecipitated by rabbit anti-FIP1 antibody NB100-74589. Rabbit IgG Aff - Purified Hu IP, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

FIP1L1 antibody

Western Blot and  Immunoprecipitation: FIP1 Antibody [NB100-74589] - Detection of Human FIP1 on HeLa whole cell lysate using NB100-74589. FIP1 was also  immunoprecipitated by rabbit anti-FIP1 antibody NB100-74588. Rabbit IgG Aff - Purified Hu IP, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

FIP1L1 antibody

Immunohistochemistry-Paraffin: FIP1L1 Antibody [NBP1-85064] - Immunohistochemical staining of human duodenum shows strong nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FIP1L1

FIP1L1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

FIP1L1

FIP1L1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

FIP1L1 overexpression lysate

FIP1L1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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