FIS1 / TTC11 antibody

Principal name

FIS1 / TTC11 antibody

Alternative names for FIS1 / TTC11 antibody

Mitochondrial fission 1 protein, FIS1 homolog, Tetratricopeptide repeat protein 11, TPR repeat protein 11

SwissProt ID

P40515 (Yeast), P84817 (Rat), Q3T0I5 (Bovin), Q9CQ92 (Mouse), Q9Y3D6 (Human)

Gene ID

51024 (FIS1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C)

Background of FIS1 / TTC11 antibody

Principal mes: CGI-135, Fis1, Fis1 homolog, H_NH0132A01.6, tetratricopeptide repeat domain 11, TPR repeat protein 11 ; Claudin 15; CLDN15; TTC11 Official Gene Symbol: TTC11 Gene ID: 51024 (Human) Gene Map Locus: 7q22.1 (Human) Fis1, a 17KDa integral membrane protein, is a novel member of mitochondrial fission machinery. It consists of a central leucine-zipper domain, a coiled-coil region, a tetratricopeptide repeat domain and a C-termil transmembrane domain. It is a human orthologue of Fis1p (S.cerevisiae) and is localized in the outer mitochondrial membrane. Fis1 acts as a pro-apoptotic factor and plays a vital role in the regulation of mitochondrial fission. It interacts with DLP1 and Mdv1p and facilitates Dnm1p recruitment to the functiol fission complex, thereby inducing apoptosis. Role of Fis1 has also been implicated in growth and division of peroxisomes. Loss of Fis1 inhibits apoptosis and results in elongation of mammalian mitochondria.

General readings

Martinou JC., et al. (2003) J Biol Chem. 278(38):36373-9.
Yoon Y., et al. (2008) Exp Cell Res. 314(19):3494-507.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FIS1 / TTC11 antibody

Sample (50 ug of whole cell lysate). A: mouse brain. 15% SDS PAGE. TA308514 diluted at 1:5000. Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FIS1 / TTC11 antibody

Immunoperoxidase of monoclonal antibody to FIS1 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml] Mouse IgG2b 1G9 Purified Hu E, P, WB
50 µg / €370.00
  Abnova Taiwan Corp.

FIS1 / TTC11 antibody

Western blot analysis of extracts of various cell lines, using FIS1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

FIS1 / TTC11 antibody

Western Blot: TTC11 Antibody [TA336435] - A. Analysis of Fis1 in A) human HeLa and B) mouse NIH 3T3 lysate using Fis1 antibody at 1:1000 dilution. B. Specificity validation of the Fis1 antibody. Fis1 was analyzed in M17 cells stably transfected with vecto Rabbit Purified Hu, Ms, Rt P, WB
0.2 ml / €325.00
  OriGene Technologies, Inc.

FIS1 / TTC11 antibody

FIS1 / TTC11 Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, IP, WB
0.1 ml / €410.00
  Acris Antibodies GmbH

FIS1 / TTC11 antibody

Prostate: Formalin-Fixed Paraffin-Embedded Human Prostate stained with anti-FIS1 Antibody Cat.-No AP09021SU-N at 1/500 dilution after heat-induced antigen retrieval. Rabbit IgG Serum Hu, Ms, Rt ICC/IF, IP, P, WB

Regular Price: 50 µl / €430.00

Special Price: 50 µl / €252.00

  Acris Antibodies GmbH

FIS1 / TTC11 antibody

TTC11 polyclonal antibody (A01), Lot # 051206JC01 Western Blot analysis of FIS1 expression in MES-SA/Dx5 ( Cat # L021V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

FIS1 / TTC11 antibody

FIS1 monoclonal antibody (M01), clone 1G9. Western Blot analysis of FIS1 expression in human liver. Mouse IgG2b 1G9 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

FIS1 / TTC11 antibody

FIS1 monoclonal antibody (M02), clone 3G6. Western Blot analysis of FIS1 expression in MCF-7 ( Cat # L046V1 ). Mouse IgG2b 3G6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

FIS1 / TTC11 antibody

FIS1 / TTC11 Mouse IgG2a 3C8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

FIS1 / TTC11 antibody

FIS1 / TTC11 Rabbit Hu, Ms, Rt C, ICC/IF, IP, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

FIS1 / TTC11 antibody

Western blot analysis of FIS1 expression in Jurkat Cell lysates. Rabbit Hu, Ms, Rt ICC/IF, WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

FIS1 / TTC11 antibody

Immunohistochemistry-Paraffin: TTC11 Antibody [NBP1-85664] - Immunohistochemical staining of human small intestine shows strong cytoplasmic granular positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FIS1 / TTC11

FIS1 / TTC11 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

FIS1 / TTC11 (1-122, His-tag)

FIS1 / TTC11 Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €670.00
  Acris Antibodies GmbH

FIS1 / TTC11 (1-122, His-tag)

FIS1 / TTC11 Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €250.00
  Acris Antibodies GmbH

FIS1 / TTC11

FIS1 / TTC11 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

FIS1 / TTC11

FIS1 / TTC11 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

FIS1 / TTC11

FIS1 / TTC11 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

FIS1 / TTC11

FIS1 / TTC11 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

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