FKBP1A / FKBP12 antibody

Principal name

FKBP1A / FKBP12 antibody

Alternative names for FKBP1A / FKBP12 antibody

PPIase FKBP1A, FK506-binding protein 1A, Rotamase, Immunophilin FKBP12, Peptidyl-prolyl cis-trans isomerase FKBP1A

SwissProt ID

O42123 (Xenla), P18203 (Bovin), P26883 (Mouse), P62942 (Human), P62943 (Rabit), Q62658 (Rat)

Gene ID

2280 (FKBP1A), 14225 (Fkbp1a), 25639

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rb (Rabbit), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunoprecipitation (IP), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of FKBP1A / FKBP12 antibody

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular sigl transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordites multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple altertively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq].

General readings

Chen H., et al. (2013) Development 140 (9), 1946-1957

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FKBP1A / FKBP12 antibody

  FKBP1A (FKBP12) mouse monoclonal antibody, clone OTI3B3 (formerly 3B3)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-FKBP1A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500557) Mouse IgG2b OTI3B3 Purified Hu F, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

FKBP1A / FKBP12 antibody

  Rabbit polyclonal anti-FKBP12 antibody  
Western blot analysis of FKBP12 expression in rat kidney tissue lysate. Rabbit Aff - Purified Bov, Hu, Ms, Rb, Rt IP, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FKBP1A / FKBP12 antibody

  Anti-FKBP1A Rabbit Polyclonal Antibody  
Predicted band size: 12 kDa . Positive control: Mouse cerebellum tissue lysate. Recommended dilution: 1/500-2000. (Gel: 12%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

FKBP1A / FKBP12 antibody

  Rabbit Polyclonal Anti-FKBP12 Antibody  
Western blot analysis of FKBP12 in A431 cell lysate with FKBP12 antibody at 1 ug/mL. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FKBP1A / FKBP12 antibody

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with FKBP12 antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

FKBP1A - human gene knockout kit via CRISPR

FKBP1A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

FKBP1A - human gene knockout kit via CRISPR

FKBP1A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

FKBP1A - human gene knockout kit via CRISPR

FKBP1A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

FKBP1A - human gene knockout kit via CRISPR

FKBP1A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Fkbp1a - mouse gene knockout kit via CRISPR

Fkbp1a - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Fkbp1a - mouse gene knockout kit via CRISPR

Fkbp1a - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Fkbp1a - mouse gene knockout kit via CRISPR

Fkbp1a - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Fkbp1a - mouse gene knockout kit via CRISPR

Fkbp1a - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FKBP1A / FKBP12 (transcript variant 12A)

  Recombinant protein of human FK506 binding protein 1A, 12kDa (FKBP1A), transcript variant 12A  
FKBP1A /  FKBP12 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

FKBP1A / FKBP12 (transcript variant 12B)

  Recombinant protein of human FK506 binding protein 1A, 12kDa (FKBP1A), transcript variant 12B  
FKBP1A /  FKBP12 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

FKBP1A / FKBP12 (1-108, His-tag)

FKBP1A /  FKBP12 Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €670.00
  Acris Antibodies GmbH

FKBP1A / FKBP12 (1-108, His-tag)

FKBP1A /  FKBP12 Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €250.00
  Acris Antibodies GmbH

FKBP1A / FKBP12 (1-108, His-tag)

FKBP1A /  FKBP12 Mouse Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

FKBP1A / FKBP12 (1-108, His-tag)

FKBP1A /  FKBP12 Mouse Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

FKBP1A overexpression lysate

FKBP1A overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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