FKBP5 / FKBP51 antibody

Principal name

FKBP5 / FKBP51 antibody

Alternative names for FKBP5 / FKBP51 antibody

AIG6, FK506-binding protein 5, FKBP54, FF1 antigen, Rotamase, Peptidyl-prolyl cis-trans isomerase FKBP5, 51 kDa FK506-binding protein, 54 kDa progesterone receptor-associated immunophilin, HSP90-binding immunophilin, Androgen-regulated protein 6

SwissProt ID

Q13451 (Human), Q64378 (Mouse)

Gene ID

2289 (FKBP5), 14229 (Fkbp5), 1228933 (apaG)

Available reactivities

Can (Canine), Hst (Hamster), Hu (Human), Ms (Mouse), Rt (Rat), Rb (Rabbit), Bov (Bovine), Chk (Chicken), Por (Porcine), Ze (Zebrafish), African clawed frog, Eq (Equine)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunoprecipitation (IP), EPair for Elisa (EPair), Frozen Sections (C)

Background of FKBP5 / FKBP51 antibody

Hsp90 is crucial to cellular signaling by its regulation of the folding, activity, and stability of a wide range of client proteins. These client protein complexes may also contain one or more cochaperones (1). One class of Hsp90-binding cochaperone is composed of proteins with a characteristic tetratricopeptide repeat (TPR) domain that forms an Hsp90 binding site. Among the TPR cochaperones of Hsp90 are Hop/Sti1, protein phosphatase PP5, and members of both the FK506- and cyclosporin A-binding families of immunophilins (2). FK506-binding protein 51 (FKBP51) and FKBP52 are large molecular weight immunophilins that are part of the mature glucocorticoid receptor (GR) heterocomplex (3). The N terminal domain of each protein binds FK506 and has peptidyl-prolyl isomerase (PPIase) activity that converts prolyl peptide bonds within target proteins from cis- to trans- proline. The C-terminal domains contain the TPR repeats involved in protein-protein interactions with the Hsp90 (4). Although FKBP52 and FKBP51 share approx. 75% sequence similarity, they affect hormone binding by glucocorticoid receptor in opposing manners and have different Hsp90-binding characteristics (3). FK506 binding protein 51 kDa (FKBP51 or otherwise referred to as FKBP54) has been identified as a progestininducible gene. This protein is predominantly expressed in murine T cells but in humans, it is abundantly expressed in numerous tissues at levels many times higher than FKBP12. The FKBP51 gene is known to be induced by glucocorticoids (5).

  1. Quick-Filters:
  2. Highly Validated (4)

Items 1 to 20 of 30 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FKBP5 / FKBP51 antibody

Immunohistochemical staining of paraffin-embedded colon tissue within the normal limits using anti-FKBP5mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500673, Dilution 1:50) Mouse IgG1 OTI3E9 Purified Hu ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

FKBP5 / FKBP51 antibody

Immunoperoxidase of purified MaxPab antibody to FKBP5 on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 3 ug/ml] Mouse Serum Hu E(detection), ICC/IF, P, WB
50 µl / €370.00
  Abnova Taiwan Corp.

FKBP5 / FKBP51 antibody

Immunoperoxidase of purified MaxPab antibody to FKBP5 on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 3 ug/ml] Mouse Purified Hu E(detection), ICC/IF, P, WB
50 µg / €370.00
  Abnova Taiwan Corp.

FKBP5 / FKBP51 antibody

Immunohistochemistry-Paraffin: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] - Immunohistochemical staining of paraffin-embedded Carcinoma of thyroid tissue using anti-FKBP5mouse monoclonal antibody. (Dilution 1:50) Mouse 3E9 Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €620.00
  Novus Biologicals Inc.

FKBP5 / FKBP51 antibody

Western blot analysis of FKBP51 in HeLa cell lysates, using a 1:1000 dilution of the antibody Mouse IgG Hi51B Purified Can, Hst, Hu, Ms, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FKBP5 / FKBP51 antibody

Host: Rabbit; Target Name: FKBP5; Sample Tissue: Thymus Tumor lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

FKBP5 / FKBP51 antibody

WB Suggested Anti-FKBP5 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

FKBP5 / FKBP51 antibody

WB was performed on whole cell lysates from mouse fibroblasts (NIH3T3) and embryonic stem cells (E14Tg2a) with the antibody against mouse FKBP51, diluted 1:500 in BSA/PBS-Tween. The molecular weight marker (in kDa) is shown on the left; the location of the protein of interest (expected size: 51 kDa) is indicated on the right. Rabbit IgG Purified Ms E
0.1 ml / €325.00
  OriGene Technologies, Inc.

FKBP5 / FKBP51 antibody

Western blot analysis of FKBP51 in HeLa cell lysates, using a 1:1000 dilution of the antibody Mouse IgG Hi51B Purified Can, Hst, Hu, Ms, Rb, Rt WB
25 µg / €230.00
  Acris Antibodies GmbH

FKBP5 / FKBP51 antibody

Western Blot analysis of FKBP5 expression in transfected 293T cell line (H00002289-T01) by FKBP5 MaxPab polyclonal antibody.

Lane 1: FKBP5 transfected lysate(51.20 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

FKBP5 / FKBP51 antibody

FKBP5 monoclonal antibody (M01), clone 3D10-1G11 Western Blot analysis of FKBP5 expression in COLO 320 HSR ( Cat # L020V1 ). Mouse IgG1 3D10-1G11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

FKBP5 / FKBP51 antibody

Immunofluorescence of monoclonal antibody to FKBP5 on HeLa cell . [antibody concentration 10 ug/ml] Mouse IgG2b 3D1-1B10 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

FKBP5 / FKBP51 antibody

Detection limit for recombinant GST tagged FKBP5 is approximately 0.03ng/ml as a capture antibody. Mouse IgG1 4H7-1F12 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

FKBP5 / FKBP51 antibody

Western blot was performed on whole cell lysates from mouse fibroblasts ( Lane 1, NIH/3T3 ) and embryonic stem cells ( Lane 2, E14Tg2a ) with Fkbp5 polyclonal antibody ( Cat # PAB14076 ), diluted 1 : 500 in BSA/PBS-Tween. Rabbit Ms E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

FKBP5 / FKBP51 antibody

Human brain; Brain, cortex; FKBP5 antibody - C-terminal region (ARP54713_P050) in Human brain cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

FKBP5 / FKBP51 antibody

Immunohistochemistry-Paraffin: FKBP5/FKBP51 Antibody [NB100-68240] - FFPE section of human breast carcinoma. Affinity purified rabbit anti-FKBP5/FKBP51 used at a dilution of 1:500.   DAB staining using Immunohistochemistry Accessory Kit Rabbit IgG Aff - Purified Hu IP, P, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

FKBP5 / FKBP51 antibody

Immunofluorescence:  FKBP51 (Hi51B) [NB110-96873] - IF localization in normal MK cells shown in red.  Courtesy of  the Hospital Henri Mondor, France Mouse IgG Hi51B Aff - Purified Can, Hst, Hu, Ms, Rb, Rt ICC/IF, WB
0.1 mg / €470.00
  Novus Biologicals Inc.

FKBP5 / FKBP51 antibody

Western Blot: FKBP5/FKBP51 Antibody [NBP1-54619] - This Anti-FKBP5 antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €440.00
  Novus Biologicals Inc.

FKBP5 / FKBP51 antibody

Immunohistochemistry-Paraffin: FKBP5/FKBP51 Antibody [NBP1-84676] - Immunohistochemical staining of human kidney shows strong cytoplasmic and nuclear positivity in cells in tubules and strong nuclear staining in cells in glomeruli. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FKBP5 / FKBP51 (transcript variant 1)

FKBP5 / FKBP51 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Items 1 to 20 of 30 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn