FMO3 antibody

Principal name

FMO3 antibody

Alternative names for FMO3 antibody

FMO form 2, FMO II, Dimethylaniline oxidase 3, Dimethylaniline monooxygenase [N-oxide-forming] 3, Hepatic flavin-containing monooxygenase 3

SwissProt ID

P31513 (Human), P32417 (Rabit), P97501 (Mouse), Q8HYJ9 (Bovin), Q95LA1 (Canfa), Q9EQ76 (Rat)

Gene ID

2328 (FMO3), 14262 (Fmo3)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rb (Rabbit), Rt (Rat), African clawed frog, GP (Guinea Pig), Gt (Goat), Ye (Yeast), Por (Porcine), Eq (Equine)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of FMO3 antibody

Flavin-containing monooxygeses (FMO) are an important class of drug-metabolizing enzymes that catalyze the DPH-dependent oxygetion of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. The human FMO gene family is composed of 5 genes and multiple pseudogenes. FMO members have distinct developmental- and tissue-specific expression patterns. The expression of this FMO3 gene, the major FMO expressed in adult liver, can vary up to 20-fold between individuals. This inter-individual variation in FMO3 expression levels is likely to have significant effects on the rate at which xenobiotics are metabolised and, therefore, is of considerable interest to the pharmaceutical industry. This transmembrane protein localizes to the endoplasmic reticulum of many tissues. Altertive splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene cause the disorder trimethylaminuria (TMAu) which is characterized by the accumulation and excretion of unmetabolized trimethylamine and a distinctive body odor. In healthy individuals, trimethylamine is primarily converted to the non odorous trimethylamine N-oxide.

General readings

Akerman, B. R., Chow, L., Forrest, S., Youil, R., Cashman, J., Treacy, E. P. Mutations in the
flavin-containing monoxygenase (sic) form 3 (FMO3) gene cause trimethylaminuria, fish odour
syndrome. (Abstract) Am. J. Hum. Genet. 61 (suppl.): A53 only, 1997.
2. Cashman, J. R., Zhang, J. Interindividual differences of human flavin-containing monooxygenase 3:
genetic polymorphisms and functional variation. Drug Metab. Dispos. 30: 1043-1052, 2002.
3. Dolphin, C. T., Janmohamed, A., Smith, R. L., Shephard, E. A., Phillips, I. R. Missense mutation in
flavin-containing mono-oxygenase 3 gene, FMO3, underlies fish-odour syndrome. Nature Genet. 17:
491-494, 1997.

Items 1 to 20 of 21 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FMO3 antibody

Western blot analysis of extracts of mouse liver cell lines, using FMO3 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

FMO3 antibody

WB Suggested Anti-FMO3 Antibody Titration: 0.2-1 ug/ml; Positive Control: OVCAR-3 cell lysate.FMO3 is strongly supported by BioGPS gene expression data to be expressed in Human OVCAR3 cells Rabbit IgG Purified Bov, GP, Gt, Hu, Ms, Rt, Ye WB
50 µg / €325.00
  OriGene Technologies, Inc.

FMO3 antibody

WB Suggested Anti-FMO3 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

FMO3 (Center) antibody

Mouse Heart; WB Suggested Anti-Fmo3 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Mouse Heart; Fmo3 antibody - middle region (AP46032PU-N) in Mouse Heart cells using Western Blot Rabbit Aff - Purified Hu, Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

FMO3 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-FMO3 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA808310)(1:150) Mouse IgG1 OTI3H1 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

FMO3 (N-term) antibody

Western blot analysis of FMO3 Antibody (N-term) (AP17395PU-N) in MDA-MB231 cell line lysates (35 µg/lane). FMO3 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

FMO3 antibody

FMO3 MaxPab polyclonal antibody. Western Blot analysis of FMO3 expression in human liver. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

FMO3 antibody

FMO3 Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

FMO3 antibody

Western Blot analysis of FMO3 expression in transfected 293T cell line (H00002328-T02) by FMO3 MaxPab polyclonal antibody.

Lane 1: FMO3 transfected lysate(60.10 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

FMO3 (N-term) antibody

Human OVCAR3; WB Suggested Anti-FMO3 Antibody Titration: 0.2-1 ug/ml. Positive Control: OVCAR-3 cell lysate. FMO3 is strongly supported by BioGPS gene expression data to be expressed in Human OVCAR3 cells.; FMO3 antibody - N-terminal region (ARP44433_P050) in Human OVCAR3 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

FMO3 antibody

Human Jurkat; WB Suggested Anti-FMO3 Antibody Titration: 0.2-1 ug/ml. Positive Control: Jurkat cell lysate; FMO3 antibody - N-terminal region (ARP44434_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rb, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

FMO3 (Center) antibody

Mouse Heart; WB Suggested Anti-Fmo3 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Mouse Heart; Fmo3 antibody - middle region (ARP44435_P050) in Mouse Heart cells using Western Blot Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

FMO3 antibody

FMO3 Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €290.00
  Boster Immunoleader

FMO3 antibody

Western  Blot:  FMO3 Antibody [NBP1-33583] – Western blot analysis of FMO3 on H1299 lysates using NBP1-33583 at a dilution of 1:1000. 30ug whole cell lysate loaded on 7.5% SDS PAGE gel. Rabbit IgG Hu ICC/IF, P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

FMO3 antibody

FMO3 Rabbit Aff - Purified Hu, Ms WB
50 µg / €440.00
  Novus Biologicals Inc.

FMO3 antibody

Immunohistochemistry-Paraffin: FMO3 Antibody [NBP1-86083] - Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

FMO3 (transcript variant 1)

FMO3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

FMO3 (transcript variant 2)

FMO3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

FMO3

FMO3 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

FMO3 (Human) IP-WB Antibody Pair

FMO3 (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Items 1 to 20 of 21 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn