FMR1 / FMRP antibody

Principal name

FMR1 / FMRP antibody

Alternative names for FMR1 / FMRP antibody

Fragile X mental retardation 1 protein, Protein FMR-1

SwissProt ID

P35922 (Mouse), Q06787 (Human), Q80WE1 (Rat), Q9NFU0 (Drome)

Gene ID

2332 (FMR1), 37528 (Fmr1), 24948

Available reactivities

Hu (Human), Dros (Drosophila), Rt (Rat), Ms (Mouse), Can (Canine), Mky (Monkey)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Frozen Sections (C), Flow Cytometry (F)

Background of FMR1 / FMRP antibody

Fragile X syndrome is the most frequent form of inherited mental retardation and is the result of transcriptional silencing of the FMR1 gene on the X chromosome. The FMR1 gene contains a distinct CpG dinucleotide repeat located in the 5' untranslated region of the gene. In fragile X syndrome this tandem repeat is substantially amplified and subjected to extensive methylation and enhanced transcriptional silencing. The FMR1 protein (or FMRP) is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle. It contains several features that are characteristics of RNA-binding proteins, including two hnRNPK homology (KH) domains and an RGG amino acid motif (RGG box). FMR1 localizes to both the nucleus and the cytoplasm and can also interact with two fragile X syndrome related factors, FXR1 and FXR2, which form heterodimers through their N-terminal coiled-coil domains. Since FMR1 contains both a nuclear localization signal and a nuclear export signal it is also implicated in the nucleocytoplasmic transport of mRNAs.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FMR1 / FMRP antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504290) Mouse IgG1 OTI1C6 Purified Can, Hu, Mky, Ms, Rt F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

FMR1 / FMRP antibody

Western blot analysis of extracts of various cell lines, using FMR1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

FMR1 / FMRP antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504291) Mouse IgG2b OTI1D10 Purified Can, Hu, Mky, Ms, Rt P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

FMR1 / FMRP antibody

Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504293) Mouse IgG2a OTI2C3 Purified Can, Hu, Mky, Ms, Rt P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

FMR1 / FMRP antibody

Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504373) Mouse IgG1 OTI5B9 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

FMR1 / FMRP antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504377) Mouse IgG1 OTI3B4 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

FMR1 / FMRP antibody

Western blot analysis of FMR1 over-expressed 293 cell line, cotransfected with FMR1 Validated Chimera RNAi ( Cat # H00002332-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with FMR1 monoclonal antibody (M01), clone 2D4 (Cat # H00002332-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control. Mouse IgG1 2D4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

FMR1 / FMRP (116-130) antibody

TA305783 (0.3ug/ml) staining of HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FMR1 / FMRP (N-term) antibody

Western blot analysis of FMR1 Antibody (N-term) (Cat. #TA324874) in mouse lung tissue lysates (35ug/lane). FMR1 (arrow) was detected using the purified Pab. Rabbit Hu, Ms WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

FMR1 / FMRP antibody

Western blot analysis of FMR1 in rat brain tissue lysate with FMR1 antibody at 1 ug/ml. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FMR1 / FMRP antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FMR1 (RC222699, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FMR1. Mouse IgG3 OTI1H9 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

FMR1 / FMRP antibody

Immunohistochemical analysis of paraffin-embedded human brain tissues, showing cytoplasmic localization with DAB staining using FMR1 antibody Cat.-No AM06321SU-N Mouse IgG1 4G9 Ascites Hu ICC/IF, P, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

FMR1 / FMRP (594-607) antibody

Immunohistochemistry Image: Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bear, Bov, Bt, Chk, Elephant, Hst, Hu, Mky, Ms, Op, Platypus, Por, Prim, Rb, Rt, Tr, Xen E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

FMR1 / FMRP (116-130) antibody

Human Brain, cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Hst, Hu, Mky, Ms, Op, Platypus, Por, Prim, Rb, Rt, Tr E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

FMR1 / FMRP antibody

FMR1 / FMRP Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

FMR1 / FMRP antibody

FMR1 / FMRP Mouse Serum Hu E
50 µl / €290.00
  Abnova Taiwan Corp.

FMR1 / FMRP antibody

Detection limit for recombinant GST tagged FMR1 is approximately 0.03ng/ml as a capture antibody. Mouse IgG1 3E11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

FMR1 / FMRP antibody

FMR1 polyclonal antibody ( Cat # PAB11527 ) ( 0.1 µg/ml ) staining of Kelly cell lysate ( 35 µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

FMR1 / FMRP antibody

FMR1 polyclonal antibody ( Cat # PAB14144 ) ( 0.3µg/ml ) staining of HeLa lysate ( 35µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

FMR1 / FMRP (C-term) antibody

FMR1 / FMRP Rabbit Aff - Purified Hu, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Items 1 to 20 of 33 total

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