Formin-binding protein 1 antibody

Principal name

Formin-binding protein 1 antibody

Alternative names for Formin-binding protein 1 antibody

FNBP1, FBP17, KIAA0554

SwissProt ID

Q6GNV5 (Xenla), Q80TY0 (Mouse), Q8R511 (Rat), Q96RU3 (Human), Q99L37 (Mouse)

Gene ID

23048 (FNBP1), 14269 (Fnbp1), 192348

Available reactivities

Hu (Human), Bt (Bat), Bov (Bovine), Can (Canine), Chk (Chicken), Eq (Equine), Fi (Fish), Hst (Hamster), Mky (Monkey), Ms (Mouse), Op (Opossum), Por (Porcine), Prim (Primate), Rt (Rat), Xen (Xenopus), Tr (Turkey), Bear

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Formin-binding protein 1 antibody

FNBP1 is a regulatory protein belonging to the formin-binding-protein family. It has a FCH domain, a coiled-coil domain, a Rho family protein-binding domain (RBD), and a SH3 domain. FNBP1 interacts with sorting nexin 2 (SNX2), tankyrase (TNkS), and dymin and is an important regulator of endocytosis. It self associates and binds to lipids to promote membrane invagition and the formation of tubules. It acts as a link between RND2 sigling and regulation of the actin cytoskeleton. FNBP1 induces neurite branching in response to ARHN. The MLL-FNBP1 fusion protein with MLL has very low transforming ability. FNBP1 is associated with acute myelogemous leukemia. FNBP1 is very highly expressed in epithelial cells, brown adipose tissue, cardiomyocytes, enteric ganglia and glucagon-producing cells of the pancreas, germ cells of the testis and brain.

General readings

Kamioka Y, Fukuhara S, Sawa H, Nagashima K, Masuda M, Matsuda M, Mochizuki N. A novel dynamin-associatingFNB molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis. J Biol Chem. 2004 Sep 17;279(38):40091-9.

19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Formin-binding protein 1 antibody

  Goat Polyclonal Antibody against FNBP1  
TA302962 staining (0.25µg/ml) of human testis lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Formin-binding protein 1 antibody

  Rabbit Polyclonal FNBP1 Antibody  
Western Blot: FNBP1 Antibody [TA336993] - analysis of FNBP1 in human liver lysate in the 1) absence and 2) presence of immunizing peptide using FNBP1 antibody at 0.1 ug/ml. Rabbit Purified Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Formin-binding protein 1 antibody

  Rabbit Polyclonal FNBP1 Antibody  
Immunohistochemistry-Paraffin: FNBP1 Antibody [TA337134] - analysis of FNBP1 in formalin-fixed, paraffin-embedded human brain tissue using an isotype control (top) and this antibody (bottom) at 5 ug/ml. Rabbit Purified Eq, Hu, Ms, Prim, Rt P
0.1 mg / €325.00
  OriGene Technologies, Inc.

Formin-binding protein 1 (132-145) antibody

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Eq, Fi, Hst, Hu, Mky, Ms, Op, Platypus, Por, Prim, Rt, Tr, Xen E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

FNBP1 - human gene knockout kit via CRISPR

FNBP1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

FNBP1 - human gene knockout kit via CRISPR

FNBP1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

FNBP1 - human gene knockout kit via CRISPR

FNBP1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

FNBP1 - human gene knockout kit via CRISPR

FNBP1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Fnbp1 - mouse gene knockout kit via CRISPR

Fnbp1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Fnbp1 - mouse gene knockout kit via CRISPR

Fnbp1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Fnbp1 - mouse gene knockout kit via CRISPR

Fnbp1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Fnbp1 - mouse gene knockout kit via CRISPR

Fnbp1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Formin-binding protein 1

  Recombinant protein of human formin binding protein 1 (FNBP1)  
Formin-binding protein 1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Fnbp1 (GFP-tagged) - Mouse formin binding protein 1 (Fnbp1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Fnbp1 (GFP-tagged) - Mouse formin binding protein 1 (Fnbp1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

Lenti ORF particles, Fnbp1 (GFP-tagged) - Mouse formin binding protein 1 (Fnbp1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Fnbp1 (GFP-tagged) - Mouse formin binding protein 1 (Fnbp1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Fnbp1 (Myc-DDK-tagged) - Mouse formin binding protein 1 (Fnbp1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Fnbp1 (Myc-DDK-tagged) - Mouse formin binding protein 1 (Fnbp1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,060.00
  OriGene Technologies, Inc.

Lenti ORF particles, Fnbp1 (Myc-DDK-tagged) - Mouse formin binding protein 1 (Fnbp1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Fnbp1 (Myc-DDK-tagged) - Mouse formin binding protein 1 (Fnbp1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Fnbp1 (GFP-tagged ORF) - Rat formin binding protein 1 (Fnbp1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Fnbp1 (GFP-tagged ORF) - Rat formin binding protein 1 (Fnbp1), 200 uL, >10^7 TU/mL  
200 µl / €1,280.00
  OriGene Technologies, Inc.

Lenti ORF particles, Fnbp1 (Myc-DDK-tagged ORF) - Rat formin binding protein 1 (Fnbp1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Fnbp1 (Myc-DDK-tagged ORF) - Rat formin binding protein 1 (Fnbp1), 200 uL, >10^7 TU/mL  
200 µl / €1,145.00
  OriGene Technologies, Inc.

19 Item(s)

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