Formin-binding protein 1 antibody

Principal name

Formin-binding protein 1 antibody

Alternative names for Formin-binding protein 1 antibody

FNBP1, FBP17, KIAA0554

SwissProt ID

Q6GNV5 (Xenla), Q80TY0 (Mouse), Q8R511 (Rat), Q96RU3 (Human), Q99L37 (Mouse)

Gene ID

23048 (FNBP1), 14269 (Fnbp1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine), Eq (Equine), Prim (Primate)

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP)

Background of Formin-binding protein 1 antibody

FNBP1 is a 617 amino acid protein that localizes to a variety of locations within the cell, including the cytoplasm, cytoskeleton, lysosome and the cell cortex, and contains one FCH domain, one REM repeat and one SH3 domain. Expressed at high levels in respiratory, reproductive and urinary systems, as well as in brown adipose tissue and epithelial cells of the gastrointestinal tract, FNBP1 interacts with Rho 7 and links the Actin cytoskeleton with Rho 7 signaling, playing a crucial role in membrane tubulation and cytoskeletal reorganization during endocytosis. Additionally, FNBP1, which exists as four alternatively spliced isoforms, enhances Actin polymerization and promotes membrane invagination and the formation of tubules. Chromosomal aberrations in the FNBP1 gene are associated with acute leukemias, suggesting a role for defective FNBP1 in carcinogenesis.

General readings

Kamioka Y, Fukuhara S, Sawa H, Nagashima K, Masuda M, Matsuda M, Mochizuki N. A novel dynamin-associatingFNB molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis. J Biol Chem. 2004 Sep 17;279(38):40091-9.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Formin-binding protein 1 antibody

TA302962 staining (0.25µg/ml) of human testis lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Formin-binding protein 1 antibody

Western Blot: FNBP1 Antibody [TA336993] - analysis of FNBP1 in human liver lysate in the 1) absence and 2) presence of immunizing peptide using FNBP1 antibody at 0.1 ug/ml. Rabbit Purified Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Formin-binding protein 1 antibody

Immunohistochemistry-Paraffin: FNBP1 Antibody [TA337134] - analysis of FNBP1 in formalin-fixed, paraffin-embedded human brain tissue using an isotype control (top) and this antibody (bottom) at 5 ug/ml. Rabbit Purified Eq, Hu, Ms, Prim, Rt P
0.1 mg / €325.00
  OriGene Technologies, Inc.

Formin-binding protein 1 (132-145) antibody

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Eq, Fi, Hst, Hu, Mky, Ms, Op, Platypus, Por, Prim, Rt, Tr, Xen E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Formin-binding protein 1 antibody

FNBP1 polyclonal antibody ( Cat # PAB6683 ) staining ( 0.25 µg/ml ) of human testis lysate ( RIPA buffer, 35 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Formin-binding protein 1 antibody

Formin-binding protein 1 Rabbit IgG Aff - Purified Ms P
0.1 mg / €680.00
  Funakoshi Co., Ltd.

Formin-binding protein 1 antibody

NB 100-1457 staining (0.25µg/ml) of Human Testis lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Formin-binding protein 1 antibody

Western Blot: FNBP1 Antibody [NBP1-47260] - Detection of Human FBP17 by Western Blot and Immunoprecipitation.  Samples:  Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells.   Antibodies: Affinity purified rabbit anti-FBP17 antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 10 mcg/mg lysate.  FBP17 was also immunoprecipitated by rabbit anti-FBP17 antibody, which recognizes a downstream epitope.  Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B). Rabbit Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Formin-binding protein 1 antibody

Western Blot: FNBP1 Antibody [NBP1-47261] - Detection of Human FBP17 by Western Blot and Immunoprecipitation.  Samples:  Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells.   Antibodies: Affinity purified rabbit anti-FBP17 antibody A302-791A used for WB at 0.4 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 10 mcg/mg lysate.  FBP17 was also immunoprecipitated by rabbit anti-FBP17 antibody A302-790A, which recognizes an upstream epitope.  For blotting immunoprecipitated FBP17, the ReliaBLOT®  Reagents and Procedures (Cat. No. WB120) were used.   Detection: Chemiluminescence with exposure times of 3 minutes (A and B). Rabbit Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Formin-binding protein 1

Formin-binding protein 1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Formin-binding protein 1

Formin-binding protein 1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Formin-binding protein 1

Formin-binding protein 1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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