Fos-related antigen 2 antibody

Principal name

Fos-related antigen 2 antibody

Alternative names for Fos-related antigen 2 antibody

FOSL2, FRA2, FRA-2

SwissProt ID

P15408 (Human), P18625 (Chick), P47930 (Mouse), P51145 (Rat)

Gene ID

2355 (FOSL2)

Available reactivities

Hu (Human), Av (Birds), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Hst (Hamster)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Frozen Sections (C), Electrophoretic Mobility Shift Assay (EMSA)

Background of Fos-related antigen 2 antibody

Cellular oncogenes, or proto-oncogenes, play pivotal roles in cellular communication pathways that regulate normal growth, development and differentiation. The cellular oncogene families fos and jun encode nuclear proteins that can function as transcription factors. The fos family of nuclear oncogenes encode cFos, FosB, (fos-related antigen) Fra1, and Fra2.
Fos and Jun dimerize to form Activator Protein-1 (AP-1), a transcriptional factor that binds to the 12-O-tetradecanoylphorbol 13-acetate (TPA) response element (TRE) of several cellular and viral genes including human collagenase, metallothionein IIa, stromelysin, interleukin 2, SV40 and polyoma. Fos and Jun contain the 'leucine-zipper' motif that allows for dimerization and an adjacent basic domain required for biological activity. The functionally active form of Fos is in a heterodimer with a member of the Jun family. While Jun family members can form functional homodimers, studies indicate that Fos family members do not self-associate and therefore do not bind DNA on their own. The various dimers differ in their ability to transactivate AP-1 dependent genes.

General readings

Huguier S et al. Transcription factor ATF2 cooperates with v-Jun to promote growth factor-independent proliferation in vitro and tumor formation in vivo. Mol Cell Biol 18:7020-9 (1998). PubMed PMID: 9819389
van Dam H et al. Autocrine growth and anchorage independence: two complementing Jun-controlled genetic programs of cellular transformation. Genes Dev 12:1227-39 (1998). PubMed PMID: 9553051
Vandel L et al. Stepwise transformation of rat embryo fibroblasts: c-Jun, JunB, or JunD can cooperate with Ras for focus formation, but a c-Jun-containing heterodimer is required for immortalization. Mol Cell Biol 16:1881-8 (1996). PubMed PMID: 8628254
Jurdic P et al. Tumor induction by v-Jun homodimers in chickens. Oncogene 11:1699-709 (1995). PubMed PMID: 7478597
Vandel L et al. Increased transforming activity of JunB and JunD by introduction of an heterologous homodimerization domain. Oncogene 10:495-507 (1995). PubMed PMID: 7845674

  1. Quick-Filters:
  2. Highly Validated (2)

Items 1 to 20 of 38 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Fos-related antigen 2 antibody

Immunofluorescence of monoclonal antibody to FOSL2 on HeLa cell. [antibody concentration 20 ug/ml] Mouse IgG2b 2B4-1C2 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Fos-related antigen 2 antibody

Human Liver; FOSL2 antibody - middle region (ARP31277_P050) in Human Liver cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze P, WB
50 µg / €350.00
  AVIVA Systems Biology

Fos-related antigen 2 (N-term) antibody

AP15566PU FRA2 antibody sttaining of Human Prostate carcinoma. Rabbit Purified Chk, Hu, Ms, Rt P, WB
0.5 ml / €360.00
  Acris Antibodies GmbH

Fos-related antigen 2 (N-term) antibody

AP15566PU FRA2 antibody sttaining of Human Prostate carcinoma. Rabbit Purified Chk, Hu, Ms, Rt P, WB
1 ml / €440.00
  Acris Antibodies GmbH

Fos-related antigen 2 (N-term) antibody

AP15566PU FRA2 antibody sttaining of Human Prostate carcinoma. Rabbit Purified Chk, Hu, Ms, Rt P, WB
0.1 ml / €180.00
  Acris Antibodies GmbH

Fos-related antigen 2 antibody

Western blot analysis of extracts from LOVO cells, using Fra-2 antibody (#TA313891).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Fos-related antigen 2 antibody

Predicted band size: 35 kDa . Positive control: 231 cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/600 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Fos-related antigen 2 (C-term) antibody

FOSL2 Antibody (C-term) (Cat. #TA324599) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the FOSL2 antibody detected the FOSL2 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Fos-related antigen 2 antibody

Western blot analysis of Fra 2 expression in LOVO cell extract Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Fos-related antigen 2 antibody

Immunohistochemistry (IHC) analyzes of Fra-2/FOSL2 antibody (Cat.-No.: AP06126PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Fos-related antigen 2 (Center) antibody

Immunohistochemistry analysis in formalin fixed andparaffin embedded human lung carcinoma reactedwith FOSL2 Antibody (Center) Cat.-No AP51699PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hst, Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Fos-related antigen 2 antibody

Fos-related antigen 2 Rabbit Serum Hu C, E, EMSA, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

Fos-related antigen 2 antibody

Fos-related antigen 2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Fos-related antigen 2 antibody

Fos-related antigen 2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Fos-related antigen 2 antibody

Western Blot analysis of FOSL2 expression in transfected 293T cell line (H00002355-T02) by FOSL2 MaxPab polyclonal antibody.

Lane 1: FOSL2 transfected lysate(35.20 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Fos-related antigen 2 antibody

Fos-related antigen 2 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Fos-related antigen 2 antibody

Immunoprecipitation of FOSL2 transfected lysate using anti-FOSL2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with FOSL2 MaxPab mouse polyclonal antibody (B01) (H00002355-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

Fos-related antigen 2 antibody

Detection limit for recombinant GST tagged FOSL2 is approximately 0.3ng/ml as a capture antibody. Mouse IgG2b 4F5-1B10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Fos-related antigen 2 antibody

Immunoperoxidase of monoclonal antibody to FOSL2 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml] Mouse IgG2a 2B2 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Fos-related antigen 2 antibody

Fos-related antigen 2 Rabbit Hu P, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Items 1 to 20 of 38 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn