FOXC1 / FKHL7 / FREAC3 antibody

Principal name

FOXC1 / FKHL7 / FREAC3 antibody

Alternative names for FOXC1 / FKHL7 / FREAC3 antibody

Forkhead box protein C1, FREAC-3, Forkhead-related protein FKHL7, Forkhead-related transcription factor 3

SwissProt ID

Q12948 (Human), Q61572 (Mouse)

Gene ID

2296 (FOXC1)

Available reactivities

Hu (Human), Ms (Mouse), Ze (Zebrafish), Bov (Bovine), Mky (Monkey), Rt (Rat), African clawed frog, Por (Porcine), Chk (Chicken), Can (Canine), Eq (Equine)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Frozen Sections (C), ChIP assay (ChIP), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of FOXC1 / FKHL7 / FREAC3 antibody

FOXC2 is a member of forkhead/winged helix transcription factor family whose members serve as key regulators in embryogenesis and cell differentiation. FOXC2 functions as a key regulator of adipocyte metabolism by increasing the sensitivity of the beta-adrenergic-cAMP-protein kinase A (PKA) signaling pathway through alteration of adipocyte PKA holoenzyme composition. Increased FOXC2 levels, induced by high fat diet, seem to counteract most of the symptoms associated with obesity. FOXC2 expression is also associated with the early stage of chondrogenic differentiation both in vivo and in vitro. FOXC2 haploinsufficiency results in Lymphedema-distichiasis (LD), an autosomal dominant disorder that classically presents as lymphedema of the limbs and double rows of eyelashes (distichiasis). Mutant mice null for FOXC2 show defects in axial and cranial skeletogenesis, suggesting a requirement of FOXC2 for skeletal tissue development.

General readings

Dagenais, S.L. et al Foxc2 is expressed in developing lymphatic vessels and other tissues associated with lymphedema-distichiasis syndrome Gene Expression Patterns :1-9 (2004).General / background references:Zhou Y et al. Identification of FOXC1 as a TGF-beta1 responsive gene and its involvement in negative regulation of cell growth. Genomics 80:465-72 (2002). PubMed PMID: 12408963

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FOXC1/2 antibody

Immunohistochemical analysis of FOXC1/2 staining in human kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Chk, Hu, Ms, Rt ICC/IF, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

FOXC1/2 antibody

Immunohistochemical analysis of FOXC1/2 staining in human kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Chk, Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

FOXC1/2 antibody

Immunohistochemical analysis of FOXC1/2 staining in human kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Chk, Hu, Ms, Rt ICC/IF, P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

FOXC1 / FKHL7 / FREAC3 (C-term) antibody

TA302875 staining (0.5µg/ml) of Human Bone Marrow lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu, Ms, Ze ChIP, E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FOXC1 / FKHL7 / FREAC3 (C-term) antibody

TA302875 staining (0.5µg/ml) of Human Bone Marrow lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu, Ms, Ze ChIP, E, P, WB
20 µg / €200.00
  Acris Antibodies GmbH

FOXC1 / FKHL7 / FREAC3 antibody

AP22375PU-N FOXC1 antibody staining of HEK293 lysate at 2µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Por E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

FOXC1 / FKHL7 / FREAC3 antibody

WB Suggested Anti-FOXC1 Antibody Titration: 5.0 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

FOXC1 / FKHL7 / FREAC3 antibody

WB Suggested Anti-FOXC1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Hu, Ms, Rt, Ze P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

FOXC1 / FKHL7 / FREAC3 antibody

WB Suggested Anti-FOXC1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Hu, Ms, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

FOXC1 / FKHL7 / FREAC3 antibody

WB Suggested Anti-Foxc1 Antibody Titration: 0.2-1 ug/ml; Positive Control: NIH/3T3 cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

FOXC1 / FKHL7 / FREAC3 (250-300) antibody

Colon: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Serum Bov, Hu, Mky, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

FOXC1 / FKHL7 / FREAC3 (+FOXC2) antibody

Immunohistochemistry analyzes of FoxC1/2 antibody (Cat.-No.: AP20435PU-N) in paraffin-embedded human prostate carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

FOXC1 / FKHL7 / FREAC3 (541-553) antibody

Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with FOXC1 antibody AP22489PU-N at 3.75 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Elephant, Fi, Hu, Mky, Ms, Op, Prim, Xen E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

FOXC1 / FKHL7 / FREAC3 antibody

FOXC1 / FKHL7 / FREAC3 Mouse IgG2b 4D11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

FOXC1 / FKHL7 / FREAC3 antibody

FOXC1 / FKHL7 / FREAC3 Mouse IgG2b 1E11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

FOXC1 / FKHL7 / FREAC3 antibody

FOXC1 polyclonal antibody ( Cat # PAB6425 ) staining ( 0.5 µg/ml ) of human bone marrow lysate ( RIPA buffer, 35 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Hu, Ms E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

FOXC1 / FKHL7 / FREAC3 antibody

FOXC1 / FKHL7 / FREAC3 Goat Hu E
0.1 mg / €400.00
  Abnova Taiwan Corp.

FOXC1 / FKHL7 / FREAC3 antibody

Western blot analysis of extracts from RAW264.7 cells, using FOXC1/2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

FOXC1 / FKHL7 / FREAC3 antibody

Western blot analysis of extracts from RAW264.7 cells, using FOXC1/2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

FOXC1 / FKHL7 / FREAC3 antibody

Human HepG2; WB Suggested Anti-FOXC1 Antibody Titration: 5.0ug/ml. Positive Control: HepG2 cell lysate; FOXC1 antibody - C-terminal region (ARP32300_T100) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Hu, Ms WB
0.1 mg / €310.00
  AVIVA Systems Biology

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